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This orthogroup contains 253 genes from 141 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 253 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10099 | PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE | 231 / 253 | 91.3% | 99.6% of 232 | ≥80% support |
| Pfam | PF02769 | AIRS_C — AIR synthase related protein, C-terminal domain | 207 / 253 | 81.8% | 91.2% of 227 | ≥80% support |
| Pfam | PF13507 | GATase_5 — CobB/CobQ-like glutamine amidotransferase domain | 191 / 253 | 75.5% | 84.1% of 227 | ≥50% support |
| Pfam | PF18072 | FGAR-AT_linker — Formylglycinamide ribonucleotide amidotransferase linker domain | 186 / 253 | 73.5% | 81.9% of 227 | ≥50% support |
| Pfam | PF18076 | FGAR-AT_N — Formylglycinamide ribonucleotide amidotransferase N-terminal | 181 / 253 | 71.5% | 79.7% of 227 | ≥50% support |
| GO | GO:0004642 Molecular Function | phosphoribosylformylglycinamidine synthase activity | 172 / 253 | 68.0% | 97.7% of 176 | ≥50% support |
| GO | GO:0006189 Biological Process | 'de novo' IMP biosynthetic process | 172 / 253 | 68.0% | 97.7% of 176 | ≥50% support |
| KEGG | K01952 | PFAS, purL — Purine metabolism | 177 / 253 | 70.0% | 97.8% of 181 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Candelabrum cocksii | ENSQNNP00000019375.1 | XP_047128981.1 | phosphoribosylformylglycinamidine synthase [Hydra vulgaris] | Q5SUR0 Phosphoribosylformylglycinamidine synthase OS=Mus musculus O | JBrowse |
| Candelabrum cocksii | ENSQNNP00000019385.1 | XP_047128981.1 | phosphoribosylformylglycinamidine synthase [Hydra vulgaris] | Q5SUR0 Phosphoribosylformylglycinamidine synthase OS=Mus musculus O | JBrowse |
