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This orthogroup contains 319 genes from 139 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 319 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR23113 | GUANINE NUCLEOTIDE EXCHANGE FACTOR | 183 / 319 | 57.4% | 77.5% of 236 | ≥50% support |
| Pfam | PF00618 | RasGEF_N — RasGEF N-terminal motif | 191 / 319 | 59.9% | 82.3% of 232 | ≥50% support |
| Pfam | PF00617 | RasGEF | 177 / 319 | 55.5% | 76.3% of 232 | ≥50% support |
| Pfam | PF00621 | RhoGEF | 173 / 319 | 54.2% | 74.6% of 232 | ≥50% support |
| GO | GO:0005085 Molecular Function | guanyl-nucleotide exchange factor activity | 239 / 319 | 74.9% | 93.4% of 256 | ≥50% support |
| GO | GO:0007264 Biological Process | small GTPase-mediated signal transduction | 191 / 319 | 59.9% | 74.6% of 256 | ≥50% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 183 / 319 | 57.4% | 71.5% of 256 | ≥50% support |
| GO | GO:0007265 Biological Process | Ras protein signal transduction | 183 / 319 | 57.4% | 71.5% of 256 | ≥50% support |
| GO | GO:0043547 Biological Process | positive regulation of GTPase activity | 183 / 319 | 57.4% | 71.5% of 256 | ≥50% support |
| GO | GO:0046982 Molecular Function | protein heterodimerization activity | 175 / 319 | 54.9% | 68.4% of 256 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Calvadosia cruxmelitensis | g1090.t1 | TSL54325.1 | Doublesex- and mab-3-related transcription factor A2 [Bagarius yarrelli] | Q4AE28 Doublesex- and mab-3-related transcription factor A2 OS=Taki | JBrowse |
| Calvadosia cruxmelitensis | g1091.t1 | XP_048584675.1 | uncharacterized protein LOC5516353 [Nematostella vectensis] | O95490 Adhesion G protein-coupled receptor L2 OS=Homo sapiens OX=96 | JBrowse |
| Calvadosia cruxmelitensis | g76.t1 | MBT4286792.1 | molecular chaperone HtpG [Deltaproteobacteria bacterium] | Q3B3E6 Chaperone protein HtpG OS=Chlorobium luteolum (strain DSM 27 | JBrowse |
| Calvadosia cruxmelitensis | g76.t2 | XP_020618128.1 | son of sevenless homolog 1-like [Orbicella faveolata] | Q62245 Son of sevenless homolog 1 OS=Mus musculus OX=10090 GN=Sos1 | JBrowse |
