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This orthogroup contains 5,952 genes from 144 species (5,953 sequences — 1 extra sequences share a gene identifier with another member, so they are not counted twice). The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 5,952 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR18945 | NEUROTRANSMITTER GATED ION CHANNEL | 5281 / 5,952 | 88.7% | 99.5% of 5,310 | ≥80% support |
| Pfam | PF02931 | Neur_chan_LBD — Neurotransmitter-gated ion-channel ligand binding domain | 5226 / 5,952 | 87.8% | 95.8% of 5,453 | ≥80% support |
| Pfam | PF02932 | Neur_chan_memb — Neurotransmitter-gated ion-channel transmembrane region | 5080 / 5,952 | 85.4% | 93.2% of 5,453 | ≥80% support |
| GO | GO:0016020 Cellular Component | membrane | 5523 / 5,952 | 92.8% | 100.0% of 5,523 | ≥80% support |
| GO | GO:0006811 Biological Process | monoatomic ion transport | 5520 / 5,952 | 92.7% | 100.0% of 5,523 | ≥80% support |
| GO | GO:0005216 Molecular Function | monoatomic ion channel activity | 5302 / 5,952 | 89.1% | 96.0% of 5,523 | ≥80% support |
| GO | GO:0034220 Biological Process | monoatomic ion transmembrane transport | 5302 / 5,952 | 89.1% | 96.0% of 5,523 | ≥80% support |
| GO | GO:0004888 Molecular Function | transmembrane signaling receptor activity | 5302 / 5,952 | 89.1% | 96.0% of 5,523 | ≥80% support |
| GO | GO:0005230 Molecular Function | extracellular ligand-gated monoatomic ion channel activity | 5287 / 5,952 | 88.8% | 95.7% of 5,523 | ≥80% support |
| GO | GO:0005887 Cellular Component | plasma membrane | 5282 / 5,952 | 88.7% | 95.6% of 5,523 | ≥80% support |
| GO | GO:0042391 Biological Process | regulation of membrane potential | 5282 / 5,952 | 88.7% | 95.6% of 5,523 | ≥80% support |
| GO | GO:0007268 Biological Process | chemical synaptic transmission | 5281 / 5,952 | 88.7% | 95.6% of 5,523 | ≥80% support |
| GO | GO:0007165 Biological Process | signal transduction | 5281 / 5,952 | 88.7% | 95.6% of 5,523 | ≥80% support |
| GO | GO:0030594 Molecular Function | neurotransmitter receptor activity | 5281 / 5,952 | 88.7% | 95.6% of 5,523 | ≥80% support |
| GO | GO:0043005 Cellular Component | neuron projection | 5281 / 5,952 | 88.7% | 95.6% of 5,523 | ≥80% support |
| GO | GO:0045202 Cellular Component | synapse | 5281 / 5,952 | 88.7% | 95.6% of 5,523 | ≥80% support |
| GO | GO:0050877 Biological Process | nervous system process | 5281 / 5,952 | 88.7% | 95.6% of 5,523 | ≥80% support |
| GO | GO:1904315 Molecular Function | transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | 5281 / 5,952 | 88.7% | 95.6% of 5,523 | ≥80% support |
| GO | GO:0005231 Molecular Function | excitatory extracellular ligand-gated monoatomic ion channel activity | 5281 / 5,952 | 88.7% | 95.6% of 5,523 | ≥80% support |
| GO | GO:0022848 Molecular Function | acetylcholine-gated monoatomic cation-selective channel activity | 3030 / 5,952 | 50.9% | 54.9% of 5,523 | ≥50% support |
| GO | GO:0045211 Cellular Component | postsynaptic membrane | 3021 / 5,952 | 50.8% | 54.7% of 5,523 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Cyphastrea salae | ENSOFVP00000007935.1 | XP_020624623.1 | neuronal acetylcholine receptor subunit alpha-7-like, partial [Orbicella faveolata] | Q494W8 CHRNA7-FAM7A fusion protein OS=Homo sapiens OX=9606 GN=CHRFA | JBrowse |
| Cyphastrea salae | ENSOFVP00000014639.1 | XP_020629736.1 | neuronal acetylcholine receptor subunit alpha-10-like isoform X2 [Orbicella faveolata] | P09478 Acetylcholine receptor subunit alpha-like 1 OS=Drosophila me | JBrowse |
| Cyphastrea salae | ENSOFVP00000014646.1 | XP_020629735.1 | neuronal acetylcholine receptor subunit alpha-10-like isoform X1 [Orbicella faveolata] | P09478 Acetylcholine receptor subunit alpha-like 1 OS=Drosophila me | JBrowse |
| Cyphastrea salae | ENSOFVP00000015520.1 | XP_020629624.1 | neuronal acetylcholine receptor subunit alpha-10-like isoform X2 [Orbicella faveolata] | Q866A2 Neuronal acetylcholine receptor subunit alpha-7 OS=Macaca mu | JBrowse |
| Cyphastrea salae | ENSOFVP00000015526.1 | XP_020629623.1 | neuronal acetylcholine receptor subunit alpha-10-like isoform X1 [Orbicella faveolata] | Q866A2 Neuronal acetylcholine receptor subunit alpha-7 OS=Macaca mu | JBrowse |
| Cyphastrea salae | ENSOFVP00000016725.1 | XP_020629575.1 | acetylcholine receptor subunit alpha-like [Orbicella faveolata] | P22770 Neuronal acetylcholine receptor subunit alpha-7 OS=Gallus ga | JBrowse |
| Cyphastrea salae | ENSOFVP00000016736.1 | XP_020629575.1 | acetylcholine receptor subunit alpha-like [Orbicella faveolata] | P22770 Neuronal acetylcholine receptor subunit alpha-7 OS=Gallus ga | JBrowse |
| Cyphastrea salae | ENSOFVP00000016950.1 | XP_020618985.1 | neuronal acetylcholine receptor subunit alpha-7-like [Orbicella faveolata] | P49582 Neuronal acetylcholine receptor subunit alpha-7 OS=Mus muscu | JBrowse |
| Cyphastrea salae | ENSOFVP00000017427.1 | XP_020615521.1 | neuronal acetylcholine receptor subunit alpha-10-like [Orbicella faveolata] | Q9I8C7 Neuronal acetylcholine receptor subunit alpha-10 OS=Gallus g | JBrowse |
| Cyphastrea salae | ENSOFVP00000017436.1 | XP_020615521.1 | neuronal acetylcholine receptor subunit alpha-10-like [Orbicella faveolata] | Q15822 Neuronal acetylcholine receptor subunit alpha-2 OS=Homo sapi | JBrowse |
| Cyphastrea salae | ENSOFVP00000017985.1 | KAJ7390532.1 | hypothetical protein OS493_024567 [Desmophyllum pertusum] | Q8R4G9 Neuronal acetylcholine receptor subunit alpha-3 OS=Mus muscu | JBrowse |
| Cyphastrea salae | ENSOFVP00000017991.1 | KAJ7390532.1 | hypothetical protein OS493_024567 [Desmophyllum pertusum] | Q8R4G9 Neuronal acetylcholine receptor subunit alpha-3 OS=Mus muscu | JBrowse |
| Cyphastrea salae | ENSOFVP00000018297.1 | XP_020629737.1 | neuronal acetylcholine receptor subunit alpha-10-like [Orbicella faveolata] | Q9I8C7 Neuronal acetylcholine receptor subunit alpha-10 OS=Gallus g | JBrowse |
| Cyphastrea salae | ENSOFVP00000018385.1 | XP_020629533.1 | neuronal acetylcholine receptor subunit alpha-10-like [Orbicella faveolata] | Q07263 Neuronal acetylcholine receptor subunit alpha-3 OS=Bos tauru | JBrowse |
| Cyphastrea salae | ENSOFVP00000018394.1 | XP_020629549.1 | neuronal acetylcholine receptor subunit alpha-10-like [Orbicella faveolata] | P09478 Acetylcholine receptor subunit alpha-like 1 OS=Drosophila me | JBrowse |
| Cyphastrea salae | ENSOFVP00000021523.1 | XP_020628199.1 | uncharacterized protein LOC110065374 [Orbicella faveolata] | Q23022 Acetylcholine receptor subunit alpha-type unc-38 OS=Caenorha | JBrowse |
| Cyphastrea salae | ENSOFVP00000021533.1 | XP_020628199.1 | uncharacterized protein LOC110065374 [Orbicella faveolata] | P54131 Neuronal acetylcholine receptor subunit alpha-7 OS=Bos tauru | JBrowse |
| Cyphastrea salae | ENSOFVP00000021542.1 | XP_020628199.1 | uncharacterized protein LOC110065374 [Orbicella faveolata] | Q9PTS8 Neuronal acetylcholine receptor subunit alpha-9 OS=Gallus ga | JBrowse |
| Cyphastrea salae | ENSOFVP00000021579.1 | XP_020601770.1 | acetylcholine receptor subunit alpha-like 1 [Orbicella faveolata] | P32297 Neuronal acetylcholine receptor subunit alpha-3 OS=Homo sapi | JBrowse |
| Cyphastrea salae | ENSOFVP00000021586.1 | XP_020601770.1 | acetylcholine receptor subunit alpha-like 1 [Orbicella faveolata] | P22770 Neuronal acetylcholine receptor subunit alpha-7 OS=Gallus ga | JBrowse |
