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This orthogroup contains 3,218 genes from 147 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 3,218 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11920 | GUANYLYL CYCLASE | 2438 / 3,218 | 75.8% | 85.7% of 2,846 | ≥50% support |
| Pfam | PF00211 | Guanylate_cyc — Adenylate and Guanylate cyclase catalytic domain | 2256 / 3,218 | 70.1% | 78.1% of 2,888 | ≥50% support |
| Pfam | PF01094 | ANF_receptor — Receptor family ligand binding region | 2207 / 3,218 | 68.6% | 76.4% of 2,888 | ≥50% support |
| Pfam | PF07714 | PK_Tyr_Ser-Thr — Protein tyrosine and serine/threonine kinase | 2123 / 3,218 | 66.0% | 73.5% of 2,888 | ≥50% support |
| GO | GO:0004383 Molecular Function | guanylate cyclase activity | 2439 / 3,218 | 75.8% | 85.9% of 2,838 | ≥50% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 2439 / 3,218 | 75.8% | 85.9% of 2,838 | ≥50% support |
| GO | GO:0001653 Molecular Function | peptide receptor activity | 2437 / 3,218 | 75.7% | 85.9% of 2,838 | ≥50% support |
| GO | GO:0004016 Molecular Function | adenylate cyclase activity | 2437 / 3,218 | 75.7% | 85.9% of 2,838 | ≥50% support |
| GO | GO:0006182 Biological Process | cGMP biosynthetic process | 2437 / 3,218 | 75.7% | 85.9% of 2,838 | ≥50% support |
| GO | GO:0007168 Biological Process | receptor guanylyl cyclase signaling pathway | 2437 / 3,218 | 75.7% | 85.9% of 2,838 | ≥50% support |
| GO | GO:0009190 Biological Process | cyclic nucleotide biosynthetic process | 2259 / 3,218 | 70.2% | 79.6% of 2,838 | ≥50% support |
| GO | GO:0035556 Biological Process | intracellular signal transduction | 2259 / 3,218 | 70.2% | 79.6% of 2,838 | ≥50% support |
| GO | GO:0004672 Molecular Function | protein kinase activity | 2162 / 3,218 | 67.2% | 76.2% of 2,838 | ≥50% support |
| GO | GO:0006468 Biological Process | protein phosphorylation | 2162 / 3,218 | 67.2% | 76.2% of 2,838 | ≥50% support |
| GO | GO:0005524 Molecular Function | ATP binding | 2127 / 3,218 | 66.1% | 75.0% of 2,838 | ≥50% support |
| GO | GO:0016849 Molecular Function | phosphorus-oxygen lyase activity | 1828 / 3,218 | 56.8% | 64.4% of 2,838 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Cyphastrea salae | ENSOFVP00000003659.1 | XP_020607147.1 | atrial natriuretic peptide receptor 1-like [Orbicella faveolata] | O02740 Retinal guanylyl cyclase 2 OS=Bos taurus OX=9913 GN=GUCY2F P | JBrowse |
| Cyphastrea salae | ENSOFVP00000003668.1 | XP_020607147.1 | atrial natriuretic peptide receptor 1-like [Orbicella faveolata] | O02740 Retinal guanylyl cyclase 2 OS=Bos taurus OX=9913 GN=GUCY2F P | JBrowse |
| Cyphastrea salae | ENSOFVP00000003683.1 | KAJ7376461.1 | hypothetical protein OS493_034449 [Desmophyllum pertusum] | P18293 Atrial natriuretic peptide receptor 1 OS=Mus musculus OX=100 | JBrowse |
| Cyphastrea salae | ENSOFVP00000003697.1 | KAJ7376461.1 | hypothetical protein OS493_034449 [Desmophyllum pertusum] | P18293 Atrial natriuretic peptide receptor 1 OS=Mus musculus OX=100 | JBrowse |
| Cyphastrea salae | ENSOFVP00000004101.1 | KAJ7392263.1 | hypothetical protein OS493_013642 [Desmophyllum pertusum] | Q7JQ32 Receptor-type guanylate cyclase Gyc76C OS=Drosophila melanog | JBrowse |
| Cyphastrea salae | ENSOFVP00000004119.1 | XP_027036228.1 | atrial natriuretic peptide receptor 2-like [Pocillopora damicornis] | P55202 Atrial natriuretic peptide receptor 2 OS=Anguilla japonica O | JBrowse |
| Cyphastrea salae | ENSOFVP00000009842.1 | XP_020632491.1 | soluble guanylate cyclase gcy-33-like isoform X2 [Orbicella faveolata] | P16066 Atrial natriuretic peptide receptor 1 OS=Homo sapiens OX=960 | JBrowse |
| Cyphastrea salae | ENSOFVP00000013289.1 | RMX38935.1 | hypothetical protein pdam_00016427 [Pocillopora damicornis] | Q07553 Guanylate cyclase 32E OS=Drosophila melanogaster OX=7227 GN= | JBrowse |
| Cyphastrea salae | ENSOFVP00000013387.1 | CAH3134366.1 | unnamed protein product [Pocillopora meandrina] | – | JBrowse |
| Cyphastrea salae | ENSOFVP00000013402.1 | CAH3134366.1 | unnamed protein product [Pocillopora meandrina] | P16066 Atrial natriuretic peptide receptor 1 OS=Homo sapiens OX=960 | JBrowse |
| Cyphastrea salae | ENSOFVP00000014648.1 | XP_020600907.1 | atrial natriuretic peptide receptor 1-like [Orbicella faveolata] | P18293 Atrial natriuretic peptide receptor 1 OS=Mus musculus OX=100 | JBrowse |
| Cyphastrea salae | ENSOFVP00000017408.1 | XP_020600816.1 | atrial natriuretic peptide receptor 1-like isoform X3 [Orbicella faveolata] | P16065 Speract receptor OS=Strongylocentrotus purpuratus OX=7668 PE | JBrowse |
| Cyphastrea salae | ENSOFVP00000017422.1 | XP_020600816.1 | atrial natriuretic peptide receptor 1-like isoform X3 [Orbicella faveolata] | P18910 Atrial natriuretic peptide receptor 1 OS=Rattus norvegicus O | JBrowse |
| Cyphastrea salae | ENSOFVP00000029384.1 | CAH3180593.1 | unnamed protein product, partial [Porites evermanni] | P18293 Atrial natriuretic peptide receptor 1 OS=Mus musculus OX=100 | JBrowse |
| Cyphastrea salae | ENSOFVP00000029398.1 | XP_027048645.1 | atrial natriuretic peptide receptor 1-like [Pocillopora damicornis] | P18293 Atrial natriuretic peptide receptor 1 OS=Mus musculus OX=100 | JBrowse |
| Cyphastrea salae | ENSOFVP00000029565.1 | XP_020618209.1 | atrial natriuretic peptide receptor 2-like [Orbicella faveolata] | P16066 Atrial natriuretic peptide receptor 1 OS=Homo sapiens OX=960 | JBrowse |
| Cyphastrea salae | ENSOFVP00000032108.1 | XP_020613215.1 | atrial natriuretic peptide receptor 1-like isoform X2 [Orbicella faveolata] | P18293 Atrial natriuretic peptide receptor 1 OS=Mus musculus OX=100 | JBrowse |
| Cyphastrea salae | ENSOFVP00000032123.1 | XP_020613211.1 | atrial natriuretic peptide receptor 1-like isoform X1 [Orbicella faveolata] | P16065 Speract receptor OS=Strongylocentrotus purpuratus OX=7668 PE | JBrowse |
| Cyphastrea salae | ENSOFVP00000032135.1 | XP_020613215.1 | atrial natriuretic peptide receptor 1-like isoform X2 [Orbicella faveolata] | P16065 Speract receptor OS=Strongylocentrotus purpuratus OX=7668 PE | JBrowse |
| Cyphastrea salae | ENSOFVP00000032892.1 | XP_020613285.1 | speract receptor-like [Orbicella faveolata] | P11528 Resact receptor OS=Arbacia punctulata OX=7641 PE=1 SV=1 | JBrowse |
