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This orthogroup contains 2,692 genes from 135 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 2,692 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR24302 | CYTOCHROME P450 FAMILY 3 | 2275 / 2,692 | 84.5% | 92.2% of 2,468 | ≥80% support |
| Pfam | PF00067 | p450 | 2468 / 2,692 | 91.7% | 100.0% of 2,469 | ≥80% support |
| GO | GO:0004497 Molecular Function | monooxygenase activity | 2481 / 2,692 | 92.2% | 100.0% of 2,481 | ≥80% support |
| GO | GO:0005506 Molecular Function | iron ion binding | 2481 / 2,692 | 92.2% | 100.0% of 2,481 | ≥80% support |
| GO | GO:0016705 Molecular Function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | 2481 / 2,692 | 92.2% | 100.0% of 2,481 | ≥80% support |
| GO | GO:0020037 Molecular Function | heme binding | 2481 / 2,692 | 92.2% | 100.0% of 2,481 | ≥80% support |
| GO | GO:0008395 Molecular Function | steroid hydroxylase activity | 2275 / 2,692 | 84.5% | 91.7% of 2,481 | ≥80% support |
| KEGG | K07424 | CYP3A — Cytochrome P450 | 1353 / 2,692 | 50.3% | 97.0% of 1,395 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Cyphastrea salae | ENSOFVP00000003445.1 | XP_020626494.1 | cytochrome P450 3A2-like [Orbicella faveolata] | Q9JMA7 Cytochrome P450 3A41 OS=Mus musculus OX=10090 GN=Cyp3a41a PE | JBrowse |
| Cyphastrea salae | ENSOFVP00000003455.1 | XP_020626494.1 | cytochrome P450 3A2-like [Orbicella faveolata] | P05183 Cytochrome P450 3A2 OS=Rattus norvegicus OX=10116 GN=Cyp3a2 | JBrowse |
| Cyphastrea salae | ENSOFVP00000005227.1 | XP_020614788.1 | cytochrome P450 3A41-like [Orbicella faveolata] | Q9JMA7 Cytochrome P450 3A41 OS=Mus musculus OX=10090 GN=Cyp3a41a PE | JBrowse |
| Cyphastrea salae | ENSOFVP00000005246.1 | RMX42116.1 | hypothetical protein pdam_00001330, partial [Pocillopora damicornis] | Q29496 Cytochrome P450 3A24 OS=Ovis aries OX=9940 GN=CYP3A24 PE=2 S | JBrowse |
| Cyphastrea salae | ENSOFVP00000007544.1 | XP_020614788.1 | cytochrome P450 3A41-like [Orbicella faveolata] | Q9JMA7 Cytochrome P450 3A41 OS=Mus musculus OX=10090 GN=Cyp3a41a PE | JBrowse |
| Cyphastrea salae | ENSOFVP00000009768.1 | XP_020626481.1 | cytochrome P450 3A2-like [Orbicella faveolata] | P05183 Cytochrome P450 3A2 OS=Rattus norvegicus OX=10116 GN=Cyp3a2 | JBrowse |
| Cyphastrea salae | ENSOFVP00000010439.1 | XP_020621676.1 | cytochrome P450 3A2-like [Orbicella faveolata] | Q9HB55 Cytochrome P450 3A43 OS=Homo sapiens OX=9606 GN=CYP3A43 PE=1 | JBrowse |
| Cyphastrea salae | ENSOFVP00000011746.1 | XP_020607814.1 | cytochrome P450 3A41-like [Orbicella faveolata] | Q64481 Cytochrome P450 3A16 OS=Mus musculus OX=10090 GN=Cyp3a16 PE= | JBrowse |
| Cyphastrea salae | ENSOFVP00000012628.1 | XP_020607806.1 | cytochrome P450 3A41-like [Orbicella faveolata] | P24557 Thromboxane-A synthase OS=Homo sapiens OX=9606 GN=TBXAS1 PE= | JBrowse |
| Cyphastrea salae | ENSOFVP00000013942.1 | XP_020607815.1 | cytochrome P450 3A6-like [Orbicella faveolata] | P36423 Thromboxane-A synthase OS=Mus musculus OX=10090 GN=Tbxas1 PE | JBrowse |
| Cyphastrea salae | ENSOFVP00000018777.1 | XP_020604908.1 | cytochrome P450 3A8-like [Orbicella faveolata] | P08684 Cytochrome P450 3A4 OS=Homo sapiens OX=9606 GN=CYP3A4 PE=1 S | JBrowse |
| Cyphastrea salae | ENSOFVP00000019033.1 | XP_020604861.1 | cytochrome P450 3A7-like isoform X1 [Orbicella faveolata] | P33268 Cytochrome P450 3A8 OS=Macaca fascicularis OX=9541 GN=CYP3A8 | JBrowse |
| Cyphastrea salae | ENSOFVP00000021279.1 | KAJ7372188.1 | Thromboxane-A synthase [Desmophyllum pertusum] | O18993 Cytochrome P450 3A21 OS=Callithrix jacchus OX=9483 GN=CYP3A2 | JBrowse |
| Cyphastrea salae | ENSOFVP00000021407.1 | XP_020604908.1 | cytochrome P450 3A8-like [Orbicella faveolata] | P33268 Cytochrome P450 3A8 OS=Macaca fascicularis OX=9541 GN=CYP3A8 | JBrowse |
| Cyphastrea salae | ENSOFVP00000021663.1 | XP_020602284.1 | cytochrome P450 3A24-like [Orbicella faveolata] | Q29496 Cytochrome P450 3A24 OS=Ovis aries OX=9940 GN=CYP3A24 PE=2 S | JBrowse |
| Cyphastrea salae | ENSOFVP00000022164.1 | KAJ7371320.1 | Thromboxane-A synthase [Desmophyllum pertusum] | Q29496 Cytochrome P450 3A24 OS=Ovis aries OX=9940 GN=CYP3A24 PE=2 S | JBrowse |
| Cyphastrea salae | ENSOFVP00000022661.1 | XP_020613941.1 | cytochrome P450 3A2-like [Orbicella faveolata] | Q64459 Cytochrome P450 3A11 OS=Mus musculus OX=10090 GN=Cyp3a11 PE= | JBrowse |
| Cyphastrea salae | ENSOFVP00000023178.1 | XP_020602396.1 | cytochrome P450 3A24-like [Orbicella faveolata] | Q29496 Cytochrome P450 3A24 OS=Ovis aries OX=9940 GN=CYP3A24 PE=2 S | JBrowse |
| Cyphastrea salae | ENSOFVP00000023291.1 | XP_020602326.1 | cytochrome P450 3A24-like [Orbicella faveolata] | P33268 Cytochrome P450 3A8 OS=Macaca fascicularis OX=9541 GN=CYP3A8 | JBrowse |
| Cyphastrea salae | ENSOFVP00000023469.1 | KAJ7375374.1 | Thromboxane-A synthase [Desmophyllum pertusum] | – | JBrowse |
