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This orthogroup contains 1,816 genes from 145 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 1,816 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11309 | FRIZZLED | 1537 / 1,816 | 84.6% | 99.2% of 1,550 | ≥80% support |
| Pfam | PF01392 | Fz | 1532 / 1,816 | 84.4% | 95.0% of 1,612 | ≥80% support |
| GO | GO:0005515 Molecular Function | protein binding | 1584 / 1,816 | 87.2% | 98.5% of 1,609 | ≥80% support |
| GO | GO:0017147 Molecular Function | Wnt-protein binding | 1537 / 1,816 | 84.6% | 95.5% of 1,609 | ≥80% support |
| GO | GO:0035567 Biological Process | non-canonical Wnt signaling pathway | 1537 / 1,816 | 84.6% | 95.5% of 1,609 | ≥80% support |
| GO | GO:0060070 Biological Process | canonical Wnt signaling pathway | 1537 / 1,816 | 84.6% | 95.5% of 1,609 | ≥80% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 1526 / 1,816 | 84.0% | 94.8% of 1,609 | ≥80% support |
| GO | GO:0016021 Cellular Component | membrane | 1515 / 1,816 | 83.4% | 94.2% of 1,609 | ≥80% support |
| GO | GO:0042813 Molecular Function | Wnt receptor activity | 1515 / 1,816 | 83.4% | 94.2% of 1,609 | ≥80% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Cyphastrea salae | ENSOFVP00000002045.1 | KAJ7357544.1 | negative regulation of sodium-dependent phosphate transport [Desmophyllum pertusum] | Q9JI33 Netrin-4 OS=Mus musculus OX=10090 GN=Ntn4 PE=1 SV=2 | JBrowse |
| Cyphastrea salae | ENSOFVP00000002051.1 | KAJ7357544.1 | negative regulation of sodium-dependent phosphate transport [Desmophyllum pertusum] | – | JBrowse |
| Cyphastrea salae | ENSOFVP00000002064.1 | KAJ7357544.1 | negative regulation of sodium-dependent phosphate transport [Desmophyllum pertusum] | Q9JI33 Netrin-4 OS=Mus musculus OX=10090 GN=Ntn4 PE=1 SV=2 | JBrowse |
| Cyphastrea salae | ENSOFVP00000002434.1 | XP_020619795.1 | secreted frizzled-related protein 3-like [Orbicella faveolata] | Q8QGP3 Carboxypeptidase Z OS=Gallus gallus OX=9031 GN=CPZ PE=1 SV=1 | JBrowse |
| Cyphastrea salae | ENSOFVP00000002449.1 | XP_020619795.1 | secreted frizzled-related protein 3-like [Orbicella faveolata] | – | JBrowse |
| Cyphastrea salae | ENSOFVP00000003760.1 | XP_020632377.1 | frizzled-4-like [Orbicella faveolata] | Q92765 Secreted frizzled-related protein 3 OS=Homo sapiens OX=9606 | JBrowse |
| Cyphastrea salae | ENSOFVP00000006476.1 | KAJ7378680.1 | hypothetical protein OS493_021984 [Desmophyllum pertusum] | – | JBrowse |
| Cyphastrea salae | ENSOFVP00000010840.1 | XP_020617724.1 | low-density lipoprotein receptor-like [Orbicella faveolata] | Q9I9M5 Frizzled-1 OS=Xenopus laevis OX=8355 GN=fzd1 PE=1 SV=1 | JBrowse |
| Cyphastrea salae | ENSOFVP00000011395.1 | XP_020612971.1 | frizzled-8-like [Orbicella faveolata] | Q13467 Frizzled-5 OS=Homo sapiens OX=9606 GN=FZD5 PE=1 SV=2 | JBrowse |
| Cyphastrea salae | ENSOFVP00000011399.1 | XP_020607220.1 | uncharacterized protein LOC110045904 [Orbicella faveolata] | Q9EQD0 Frizzled-5 OS=Mus musculus OX=10090 GN=Fzd5 PE=1 SV=3 | JBrowse |
| Cyphastrea salae | ENSOFVP00000028135.1 | XP_020623357.1 | frizzled-4-like [Orbicella faveolata] | Q9IA05 Frizzled-4 OS=Gallus gallus OX=9031 GN=FZD4 PE=1 SV=1 | JBrowse |
| Cyphastrea salae | ENSOFVP00000031532.1 | XP_020623341.1 | frizzled-9-like [Orbicella faveolata] | Q9W742 Frizzled-10-B OS=Xenopus laevis OX=8355 GN=fzd10-b PE=2 SV=1 | JBrowse |
| Cyphastrea salae | ENSOFVP00000031535.1 | XP_020623341.1 | frizzled-9-like [Orbicella faveolata] | Q9PWH2 Frizzled-10 OS=Gallus gallus OX=9031 GN=FZD10 PE=1 SV=1 | JBrowse |
| Cyphastrea salae | ENSOFVP00000031581.1 | XP_020606971.1 | atrial natriuretic peptide-converting enzyme-like [Orbicella faveolata] | Q24760 Frizzled OS=Drosophila virilis OX=7244 GN=fz PE=2 SV=3 | JBrowse |