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This orthogroup contains 1,515 genes from 145 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 1,515 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11256 | BCL-2 RELATED | 1339 / 1,515 | 88.4% | 99.8% of 1,342 | ≥80% support |
| Pfam | PF00452 | Bcl-2 | 1343 / 1,515 | 88.7% | 99.9% of 1,344 | ≥80% support |
| GO | GO:0042981 Biological Process | regulation of apoptotic process | 1350 / 1,515 | 89.1% | 99.9% of 1,351 | ≥80% support |
| GO | GO:0005741 Cellular Component | mitochondrial outer membrane | 1339 / 1,515 | 88.4% | 99.1% of 1,351 | ≥80% support |
| GO | GO:0008630 Biological Process | intrinsic apoptotic signaling pathway in response to DNA damage | 1339 / 1,515 | 88.4% | 99.1% of 1,351 | ≥80% support |
| GO | GO:0042803 Molecular Function | protein homodimerization activity | 1339 / 1,515 | 88.4% | 99.1% of 1,351 | ≥80% support |
| GO | GO:0046982 Molecular Function | protein heterodimerization activity | 1339 / 1,515 | 88.4% | 99.1% of 1,351 | ≥80% support |
| GO | GO:0097192 Biological Process | extrinsic apoptotic signaling pathway in absence of ligand | 1339 / 1,515 | 88.4% | 99.1% of 1,351 | ≥80% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Cyphastrea salae | ENSOFVP00000008552.1 | KAJ7352866.1 | hypothetical protein OS493_033129 [Desmophyllum pertusum] | Q91828 Apoptosis regulator R11 OS=Xenopus laevis OX=8355 PE=2 SV=1 | JBrowse |
| Cyphastrea salae | ENSOFVP00000008975.1 | XP_020629000.1 | induced myeloid leukemia cell differentiation protein Mcl-1 homolog [Orbicella faveolata] | Q9JJV8 Apoptosis regulator Bcl-2 OS=Cricetulus griseus OX=10029 GN= | JBrowse |
| Cyphastrea salae | ENSOFVP00000016365.1 | XP_020600881.1 | bcl-2-like protein 1 [Orbicella faveolata] | Q64373 Bcl-2-like protein 1 OS=Mus musculus OX=10090 GN=Bcl2l1 PE=1 | JBrowse |
| Cyphastrea salae | ENSOFVP00000016373.1 | XP_020600881.1 | bcl-2-like protein 1 [Orbicella faveolata] | Q64373 Bcl-2-like protein 1 OS=Mus musculus OX=10090 GN=Bcl2l1 PE=1 | JBrowse |
| Cyphastrea salae | ENSOFVP00000017042.1 | XP_020631944.1 | apoptosis regulator R1-like [Orbicella faveolata] | Q91827 Apoptosis regulator R1 (Fragment) OS=Xenopus laevis OX=8355 | JBrowse |
| Cyphastrea salae | ENSOFVP00000018717.1 | XP_020629527.1 | bcl-2-related protein A1-like [Orbicella faveolata] | – | JBrowse |
| Cyphastrea salae | ENSOFVP00000021156.1 | XP_020601942.1 | bcl-2 homologous antagonist/killer-like [Orbicella faveolata] | Q16611 Bcl-2 homologous antagonist/killer OS=Homo sapiens OX=9606 G | JBrowse |
| Cyphastrea salae | ENSOFVP00000023924.1 | XP_020601885.1 | apoptosis regulator R1-like [Orbicella faveolata] | Q16611 Bcl-2 homologous antagonist/killer OS=Homo sapiens OX=9606 G | JBrowse |
| Cyphastrea salae | ENSOFVP00000033869.1 | XP_020620765.1 | apoptosis regulator BAX-like [Orbicella faveolata] | Q07812 Apoptosis regulator BAX OS=Homo sapiens OX=9606 GN=BAX PE=1 | JBrowse |
