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This orthogroup contains 1,386 genes from 148 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 1,386 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR23255 | TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II | 1190 / 1,386 | 85.9% | 100.0% of 1,190 | ≥80% support |
| GO | GO:0004675 Molecular Function | transmembrane receptor protein serine/threonine kinase activity | 1200 / 1,386 | 86.6% | 99.9% of 1,201 | ≥80% support |
| GO | GO:0016020 Cellular Component | membrane | 1200 / 1,386 | 86.6% | 99.9% of 1,201 | ≥80% support |
| GO | GO:0005524 Molecular Function | ATP binding | 1191 / 1,386 | 85.9% | 99.2% of 1,201 | ≥80% support |
| GO | GO:0006468 Biological Process | protein phosphorylation | 1191 / 1,386 | 85.9% | 99.2% of 1,201 | ≥80% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 1190 / 1,386 | 85.9% | 99.1% of 1,201 | ≥80% support |
| GO | GO:0007178 Biological Process | cell surface receptor protein serine/threonine kinase signaling pathway | 1190 / 1,386 | 85.9% | 99.1% of 1,201 | ≥80% support |
| GO | GO:0004674 Molecular Function | protein serine/threonine kinase activity | 1180 / 1,386 | 85.1% | 98.3% of 1,201 | ≥80% support |
| GO | GO:0043235 Cellular Component | receptor complex | 1180 / 1,386 | 85.1% | 98.3% of 1,201 | ≥80% support |
| GO | GO:0071363 Biological Process | cellular response to growth factor stimulus | 1180 / 1,386 | 85.1% | 98.3% of 1,201 | ≥80% support |
| GO | GO:0004672 Molecular Function | protein kinase activity | 1172 / 1,386 | 84.6% | 97.6% of 1,201 | ≥80% support |
| Pfam | PF07714 | PK_Tyr_Ser-Thr — Protein tyrosine and serine/threonine kinase | 793 / 1,386 | 57.2% | 68.1% of 1,165 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Cyphastrea salae | ENSOFVP00000002598.1 | XP_020613449.1 | bone morphogenetic protein receptor type-1B-like [Orbicella faveolata] | P36898 Bone morphogenetic protein receptor type-1B OS=Mus musculus | JBrowse |
| Cyphastrea salae | ENSOFVP00000011804.1 | XP_029194612.1 | bone morphogenetic protein receptor type-1A-like isoform X2 [Acropora millepora] | P36894 Bone morphogenetic protein receptor type-1A OS=Homo sapiens | JBrowse |
| Cyphastrea salae | ENSOFVP00000011977.1 | XP_020612956.1 | TGF-beta receptor type-1-like isoform X1 [Orbicella faveolata] | O46680 TGF-beta receptor type-1 OS=Bos taurus OX=9913 GN=TGFBR1 PE= | JBrowse |
| Cyphastrea salae | ENSOFVP00000013361.1 | XP_020612995.1 | activin receptor type-1-like [Orbicella faveolata] | P80204 TGF-beta receptor type-1 OS=Rattus norvegicus OX=10116 GN=Tg | JBrowse |
| Cyphastrea salae | ENSOFVP00000022356.1 | XP_020615843.1 | bone morphogenetic protein receptor type-2-like [Orbicella faveolata] | – | JBrowse |
| Cyphastrea salae | ENSOFVP00000023758.1 | XP_020615866.1 | TGF-beta receptor type-2-like [Orbicella faveolata] | O46680 TGF-beta receptor type-1 OS=Bos taurus OX=9913 GN=TGFBR1 PE= | JBrowse |
| Cyphastrea salae | ENSOFVP00000023770.1 | KAJ7354771.1 | TGF-beta receptor type-2 [Desmophyllum pertusum] | P37173 TGF-beta receptor type-2 OS=Homo sapiens OX=9606 GN=TGFBR2 P | JBrowse |
| Cyphastrea salae | ENSOFVP00000024909.1 | XP_020615843.1 | bone morphogenetic protein receptor type-2-like [Orbicella faveolata] | Q13873 Bone morphogenetic protein receptor type-2 OS=Homo sapiens O | JBrowse |
| Cyphastrea salae | ENSOFVP00000025380.1 | XP_020615849.1 | activin receptor type-2A-like isoform X2 [Orbicella faveolata] | Q90669 Activin receptor type-2A OS=Gallus gallus OX=9031 GN=ACVR2A | JBrowse |
| Cyphastrea salae | ENSOFVP00000025389.1 | XP_020615848.1 | activin receptor type-2A-like isoform X1 [Orbicella faveolata] | P27039 Activin receptor type-2A OS=Xenopus laevis OX=8355 GN=acvr2a | JBrowse |
