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This orthogroup contains 1,378 genes from 143 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 1,378 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11412 | MACROGLOBULIN / COMPLEMENT | 1180 / 1,378 | 85.6% | 99.8% of 1,182 | ≥80% support |
| Pfam | PF07678 | TED_complement — A-macroglobulin TED domain | 776 / 1,378 | 56.3% | 66.0% of 1,175 | ≥50% support |
| Pfam | PF07703 | A2M_BRD — Alpha-2-macroglobulin bait region domain | 728 / 1,378 | 52.8% | 62.0% of 1,175 | ≥50% support |
| Pfam | PF00207 | A2M — Alpha-2-macroglobulin family | 707 / 1,378 | 51.3% | 60.2% of 1,175 | ≥50% support |
| GO | GO:0004866 Molecular Function | endopeptidase inhibitor activity | 869 / 1,378 | 63.1% | 83.4% of 1,042 | ≥50% support |
| GO | GO:0005615 Cellular Component | extracellular space | 776 / 1,378 | 56.3% | 74.5% of 1,042 | ≥50% support |
| GO | GO:0005576 Cellular Component | extracellular region | 698 / 1,378 | 50.7% | 67.0% of 1,042 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Cyphastrea salae | ENSOFVP00000002894.1 | XP_020623135.1 | CD109 antigen-like [Orbicella faveolata] | Q63041 Alpha-1-macroglobulin OS=Rattus norvegicus OX=10116 GN=A1m P | JBrowse |
| Cyphastrea salae | ENSOFVP00000002918.1 | XP_020623135.1 | CD109 antigen-like [Orbicella faveolata] | Q6YHK3 CD109 antigen OS=Homo sapiens OX=9606 GN=CD109 PE=1 SV=2 | JBrowse |
| Cyphastrea salae | ENSOFVP00000002942.1 | XP_020623135.1 | CD109 antigen-like [Orbicella faveolata] | Q6YHK3 CD109 antigen OS=Homo sapiens OX=9606 GN=CD109 PE=1 SV=2 | JBrowse |
| Cyphastrea salae | ENSOFVP00000017306.1 | XP_020628881.1 | alpha-2-macroglobulin-like isoform X3 [Orbicella faveolata] | – | JBrowse |
| Cyphastrea salae | ENSOFVP00000017654.1 | XP_020628879.1 | alpha-2-macroglobulin-like isoform X1 [Orbicella faveolata] | Q61838 Pregnancy zone protein OS=Mus musculus OX=10090 GN=Pzp PE=1 | JBrowse |
