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This orthogroup contains 1,009 genes from 146 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 1,009 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10390 | HOMEOBOX PROTEIN SIX | 865 / 1,009 | 85.7% | 98.2% of 881 | ≥80% support |
| Pfam | PF16878 | SIX1_SD — Transcriptional regulator, SIX1, N-terminal SD domain | 880 / 1,009 | 87.2% | 97.9% of 899 | ≥80% support |
| GO | GO:0000978 Molecular Function | RNA polymerase II cis-regulatory region sequence-specific DNA binding | 880 / 1,009 | 87.2% | 99.7% of 883 | ≥80% support |
| GO | GO:0006357 Biological Process | regulation of transcription by RNA polymerase II | 880 / 1,009 | 87.2% | 99.7% of 883 | ≥80% support |
| GO | GO:0003677 Molecular Function | DNA binding | 879 / 1,009 | 87.1% | 99.6% of 883 | ≥80% support |
| GO | GO:0000981 Molecular Function | DNA-binding transcription factor activity, RNA polymerase II-specific | 873 / 1,009 | 86.5% | 98.9% of 883 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 865 / 1,009 | 85.7% | 98.0% of 883 | ≥80% support |
| GO | GO:0005667 Cellular Component | transcription regulator complex | 865 / 1,009 | 85.7% | 98.0% of 883 | ≥80% support |
| Pfam | PF00046 | Homeodomain | 526 / 1,009 | 52.1% | 58.5% of 899 | ≥50% support |
| GO | GO:0006355 Biological Process | regulation of DNA-templated transcription | 644 / 1,009 | 63.8% | 72.9% of 883 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Cyphastrea salae | ENSOFVP00000002321.1 | XP_022782439.1 | homeobox protein SIX2-like [Stylophora pistillata] | – | JBrowse |
| Cyphastrea salae | ENSOFVP00000011449.1 | XP_020605711.1 | homeobox protein SIX6-like [Orbicella faveolata] | Q61321 Homeobox protein SIX4 OS=Mus musculus OX=10090 GN=Six4 PE=1 | JBrowse |
| Cyphastrea salae | ENSOFVP00000011867.1 | XP_020605799.1 | homeobox protein six1b-like [Orbicella faveolata] | Q6NZ04 Homeobox protein six1b OS=Danio rerio OX=7955 GN=six1b PE=1 | JBrowse |
| Cyphastrea salae | ENSOFVP00000011881.1 | XP_022791262.1 | homeobox protein SIX3 isoform X2 [Stylophora pistillata] | O42406 Homeobox protein SIX3 OS=Gallus gallus OX=9031 GN=SIX3 PE=1 | JBrowse |
| Cyphastrea salae | ENSOFVP00000013925.1 | XP_020605725.1 | homeobox protein six1-like isoform X2 [Orbicella faveolata] | Q9I8H0 Homeobox protein six1 OS=Xenopus laevis OX=8355 GN=six1 PE=2 | JBrowse |
| Cyphastrea salae | ENSOFVP00000017179.1 | XP_020619199.1 | homeobox protein SIX6-like [Orbicella faveolata] | A6NDR6 Putative homeobox protein Meis3-like 1 OS=Homo sapiens OX=96 | JBrowse |
