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This orthogroup contains 814 genes from 141 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 814 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| Pfam | PF00067 | p450 | 709 / 814 | 87.1% | 99.7% of 711 | ≥80% support |
| GO | GO:0004497 Molecular Function | monooxygenase activity | 722 / 814 | 88.7% | 99.9% of 723 | ≥80% support |
| GO | GO:0005506 Molecular Function | iron ion binding | 722 / 814 | 88.7% | 99.9% of 723 | ≥80% support |
| GO | GO:0016705 Molecular Function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | 722 / 814 | 88.7% | 99.9% of 723 | ≥80% support |
| GO | GO:0020037 Molecular Function | heme binding | 722 / 814 | 88.7% | 99.9% of 723 | ≥80% support |
| PANTHER | PTHR24291 | CYTOCHROME P450 FAMILY 4 | 648 / 814 | 79.6% | 92.6% of 700 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Cyphastrea salae | ENSOFVP00000020704.1 | XP_020604892.1 | cytochrome P450 4c21-like [Orbicella faveolata] | Q64481 Cytochrome P450 3A16 OS=Mus musculus OX=10090 GN=Cyp3a16 PE= | JBrowse |
| Cyphastrea salae | ENSOFVP00000020885.1 | XP_020604870.1 | cytochrome P450 4F5-like [Orbicella faveolata] | Q9HCS2 Cytochrome P450 4F12 OS=Homo sapiens OX=9606 GN=CYP4F12 PE=1 | JBrowse |
| Cyphastrea salae | ENSOFVP00000029702.1 | XP_020606983.1 | cytochrome P450 4A25-like isoform X1 [Orbicella faveolata] | Q27589 Cytochrome P450 4d2 OS=Drosophila melanogaster OX=7227 GN=Cy | JBrowse |