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This orthogroup contains 507 genes from 143 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 507 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11347 | CYCLIC NUCLEOTIDE PHOSPHODIESTERASE | 437 / 507 | 86.2% | 99.8% of 438 | ≥80% support |
| GO | GO:0004114 Molecular Function | 3',5'-cyclic-nucleotide phosphodiesterase activity | 437 / 507 | 86.2% | 96.5% of 453 | ≥80% support |
| GO | GO:0007165 Biological Process | signal transduction | 437 / 507 | 86.2% | 96.5% of 453 | ≥80% support |
| GO | GO:0004118 Molecular Function | 3',5'-cGMP-stimulated cyclic-nucleotide phosphodiesterase activity | 433 / 507 | 85.4% | 95.6% of 453 | ≥80% support |
| GO | GO:0010754 Biological Process | negative regulation of cGMP-mediated signaling | 433 / 507 | 85.4% | 95.6% of 453 | ≥80% support |
| Pfam | PF00233 | PDEase_I — 3'5'-cyclic nucleotide phosphodiesterase | 402 / 507 | 79.3% | 88.7% of 453 | ≥50% support |
| Pfam | PF01590 | GAF | 392 / 507 | 77.3% | 86.5% of 453 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 398 / 507 | 78.5% | 87.9% of 453 | ≥50% support |
| GO | GO:0008081 Molecular Function | phosphoric diester hydrolase activity | 389 / 507 | 76.7% | 85.9% of 453 | ≥50% support |
| KEGG | K18438 | PDE10 — Morphine addiction | 286 / 507 | 56.4% | 97.3% of 294 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Cyphastrea salae | ENSOFVP00000010510.1 | XP_027040987.1 | probable 3',5'-cyclic phosphodiesterase pde-5 [Pocillopora damicornis] | P91119 Probable 3',5'-cyclic phosphodiesterase pde-5 OS=Caenorhabdi | JBrowse |
| Cyphastrea salae | ENSOFVP00000028324.1 | RMX48743.1 | hypothetical protein pdam_00001522 [Pocillopora damicornis] | Q8CA95 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase | JBrowse |
