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This orthogroup contains 450 genes from 96 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 450 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR18945 | NEUROTRANSMITTER GATED ION CHANNEL | 377 / 450 | 83.8% | 98.7% of 382 | ≥80% support |
| GO | GO:0006811 Biological Process | monoatomic ion transport | 432 / 450 | 96.0% | 100.0% of 432 | ≥80% support |
| GO | GO:0016020 Cellular Component | membrane | 432 / 450 | 96.0% | 100.0% of 432 | ≥80% support |
| GO | GO:0005216 Molecular Function | monoatomic ion channel activity | 406 / 450 | 90.2% | 94.0% of 432 | ≥80% support |
| GO | GO:0034220 Biological Process | monoatomic ion transmembrane transport | 406 / 450 | 90.2% | 94.0% of 432 | ≥80% support |
| GO | GO:0004888 Molecular Function | transmembrane signaling receptor activity | 406 / 450 | 90.2% | 94.0% of 432 | ≥80% support |
| GO | GO:0030594 Molecular Function | neurotransmitter receptor activity | 377 / 450 | 83.8% | 87.3% of 432 | ≥80% support |
| GO | GO:0050877 Biological Process | nervous system process | 377 / 450 | 83.8% | 87.3% of 432 | ≥80% support |
| GO | GO:0045202 Cellular Component | synapse | 377 / 450 | 83.8% | 87.3% of 432 | ≥80% support |
| GO | GO:0043005 Cellular Component | neuron projection | 377 / 450 | 83.8% | 87.3% of 432 | ≥80% support |
| GO | GO:0042391 Biological Process | regulation of membrane potential | 377 / 450 | 83.8% | 87.3% of 432 | ≥80% support |
| GO | GO:0007268 Biological Process | chemical synaptic transmission | 377 / 450 | 83.8% | 87.3% of 432 | ≥80% support |
| GO | GO:0007165 Biological Process | signal transduction | 377 / 450 | 83.8% | 87.3% of 432 | ≥80% support |
| GO | GO:0005887 Cellular Component | plasma membrane | 377 / 450 | 83.8% | 87.3% of 432 | ≥80% support |
| GO | GO:0005230 Molecular Function | extracellular ligand-gated monoatomic ion channel activity | 366 / 450 | 81.3% | 84.7% of 432 | ≥80% support |
| Pfam | PF02932 | Neur_chan_memb — Neurotransmitter-gated ion-channel transmembrane region | 352 / 450 | 78.2% | 84.8% of 415 | ≥50% support |
| Pfam | PF02931 | Neur_chan_LBD — Neurotransmitter-gated ion-channel ligand binding domain | 349 / 450 | 77.6% | 84.1% of 415 | ≥50% support |
| GO | GO:0005254 Molecular Function | chloride channel activity | 357 / 450 | 79.3% | 82.6% of 432 | ≥50% support |
| GO | GO:0005231 Molecular Function | excitatory extracellular ligand-gated monoatomic ion channel activity | 357 / 450 | 79.3% | 82.6% of 432 | ≥50% support |
| GO | GO:1902476 Biological Process | chloride transmembrane transport | 357 / 450 | 79.3% | 82.6% of 432 | ≥50% support |
| GO | GO:1904315 Molecular Function | transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | 357 / 450 | 79.3% | 82.6% of 432 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Cyphastrea salae | ENSOFVP00000006441.1 | XP_020615628.1 | gamma-aminobutyric acid receptor subunit beta-3-like [Orbicella faveolata] | P24046 Gamma-aminobutyric acid receptor subunit rho-1 OS=Homo sapie | JBrowse |
| Cyphastrea salae | ENSOFVP00000007866.1 | XP_022807880.1 | gamma-aminobutyric acid receptor subunit pi-like [Stylophora pistillata] | – | JBrowse |
| Cyphastrea salae | ENSOFVP00000010201.1 | XP_020619790.1 | gamma-aminobutyric acid receptor subunit rho-2-like [Orbicella faveolata] | – | JBrowse |
| Cyphastrea salae | ENSOFVP00000010205.1 | RMX41503.1 | hypothetical protein pdam_00012265 [Pocillopora damicornis] | P26714 Gamma-aminobutyric acid receptor subunit beta OS=Lymnaea sta | JBrowse |
| Cyphastrea salae | ENSOFVP00000010987.1 | KAJ7378987.1 | hypothetical protein OS493_018781 [Desmophyllum pertusum] | – | JBrowse |
| Cyphastrea salae | ENSOFVP00000011331.1 | XP_020610016.1 | gamma-aminobutyric acid receptor subunit alpha-5-like [Orbicella faveolata] | – | JBrowse |
| Cyphastrea salae | ENSOFVP00000012428.1 | KAJ7378664.1 | hypothetical protein OS493_021966 [Desmophyllum pertusum] | O00591 Gamma-aminobutyric acid receptor subunit pi OS=Homo sapiens | JBrowse |
