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This orthogroup contains 428 genes from 147 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 428 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR12081 | TRANSCRIPTION FACTOR E2F | 376 / 428 | 87.9% | 99.7% of 377 | ≥80% support |
| Pfam | PF02319 | E2F_TDP — E2F/DP family winged-helix DNA-binding domain | 365 / 428 | 85.3% | 96.3% of 379 | ≥80% support |
| GO | GO:0000978 Molecular Function | RNA polymerase II cis-regulatory region sequence-specific DNA binding | 376 / 428 | 87.9% | 99.2% of 379 | ≥80% support |
| GO | GO:0000981 Molecular Function | DNA-binding transcription factor activity, RNA polymerase II-specific | 376 / 428 | 87.9% | 99.2% of 379 | ≥80% support |
| GO | GO:0006357 Biological Process | regulation of transcription by RNA polymerase II | 376 / 428 | 87.9% | 99.2% of 379 | ≥80% support |
| GO | GO:0090575 Cellular Component | RNA polymerase II transcription regulator complex | 376 / 428 | 87.9% | 99.2% of 379 | ≥80% support |
| GO | GO:0005667 Cellular Component | transcription regulator complex | 365 / 428 | 85.3% | 96.3% of 379 | ≥80% support |
| GO | GO:0006355 Biological Process | regulation of DNA-templated transcription | 365 / 428 | 85.3% | 96.3% of 379 | ≥80% support |
| Pfam | PF16421 | E2F_CC-MB — E2F transcription factor CC-MB domain | 339 / 428 | 79.2% | 89.5% of 379 | ≥50% support |
| GO | GO:0046983 Molecular Function | protein dimerization activity | 339 / 428 | 79.2% | 89.5% of 379 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Cyphastrea salae | ENSOFVP00000002406.1 | XP_020609755.1 | transcription factor E2F5-like isoform X1 [Orbicella faveolata] | Q6DE14 Transcription factor E2F4 OS=Xenopus laevis OX=8355 GN=e2f4 | JBrowse |
| Cyphastrea salae | ENSOFVP00000031694.1 | XP_020609724.1 | transcription factor E2F6-like [Orbicella faveolata] | O00716 Transcription factor E2F3 OS=Homo sapiens OX=9606 GN=E2F3 PE | JBrowse |
