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This orthogroup contains 421 genes from 142 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 421 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11085 | NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED | 349 / 421 | 82.9% | 99.7% of 350 | ≥80% support |
| Pfam | PF02146 | SIR2 | 350 / 421 | 83.1% | 100.0% of 350 | ≥80% support |
| GO | GO:0070403 Molecular Function | NAD+ binding | 350 / 421 | 83.1% | 100.0% of 350 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 349 / 421 | 82.9% | 99.7% of 350 | ≥80% support |
| GO | GO:0017136 Molecular Function | histone deacetylase activity, NAD-dependent | 349 / 421 | 82.9% | 99.7% of 350 | ≥80% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Cyphastrea salae | ENSOFVP00000027458.1 | XP_020605893.1 | NAD-dependent protein deacetylase sirtuin-2-like [Orbicella faveolata] | Q5RBF1 NAD-dependent protein deacetylase sirtuin-2 OS=Pongo abelii | JBrowse |
| Cyphastrea salae | ENSOFVP00000027472.1 | XP_022806417.1 | NAD-dependent protein deacetylase sirtuin-2-like [Stylophora pistillata] | Q8VDQ8 NAD-dependent protein deacetylase sirtuin-2 OS=Mus musculus | JBrowse |
| Cyphastrea salae | ENSOFVP00000035165.1 | XP_020605702.1 | NAD-dependent protein deacetylase hst2-like isoform X2 [Orbicella faveolata] | Q9NTG7 NAD-dependent protein deacetylase sirtuin-3, mitochondrial O | JBrowse |
