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This orthogroup contains 351 genes from 142 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 351 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10170 | HUNTINGTON DISEASE PROTEIN | 297 / 351 | 84.6% | 99.0% of 300 | ≥80% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 298 / 351 | 84.9% | 99.3% of 300 | ≥80% support |
| Pfam | PF20927 | Htt_C-HEAT — Huntingtin, C-terminal HEAT | 221 / 351 | 63.0% | 75.7% of 292 | ≥50% support |
| Pfam | PF12372 | Htt_N-HEAT — Huntingtin, N-terminal HEAT | 215 / 351 | 61.3% | 73.6% of 292 | ≥50% support |
| Pfam | PF20925 | Htt_bridge — Huntingtin, bridge | 198 / 351 | 56.4% | 67.8% of 292 | ≥50% support |
| Pfam | PF20926 | Htt_N-HEAT_1 — Huntingtin, N-terminal HEAT 1 | 184 / 351 | 52.4% | 63.0% of 292 | ≥50% support |
| GO | GO:0005634 Cellular Component | nucleus | 231 / 351 | 65.8% | 77.0% of 300 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Cyphastrea salae | ENSOFVP00000019509.1 | CAH3189303.1 | unnamed protein product, partial [Porites evermanni] | P42859 Huntingtin OS=Mus musculus OX=10090 GN=Htt PE=1 SV=2 | JBrowse |
| Cyphastrea salae | ENSOFVP00000019539.1 | XP_020607083.1 | LOW QUALITY PROTEIN: huntingtin-like [Orbicella faveolata] | P42859 Huntingtin OS=Mus musculus OX=10090 GN=Htt PE=1 SV=2 | JBrowse |
