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This orthogroup contains 329 genes from 113 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 329 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR28657 | INDOLEAMINE 2,3-DIOXYGENASE | 300 / 329 | 91.2% | 100.0% of 300 | ≥80% support |
| Pfam | PF01231 | IDO — Indoleamine 2,3-dioxygenase | 302 / 329 | 91.8% | 100.0% of 302 | ≥80% support |
| GO | GO:0019441 Biological Process | tryptophan catabolic process to kynurenine | 304 / 329 | 92.4% | 100.0% of 304 | ≥80% support |
| GO | GO:0020037 Molecular Function | heme binding | 304 / 329 | 92.4% | 100.0% of 304 | ≥80% support |
| GO | GO:0046872 Molecular Function | metal ion binding | 304 / 329 | 92.4% | 100.0% of 304 | ≥80% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 294 / 329 | 89.4% | 96.7% of 304 | ≥80% support |
| GO | GO:0033754 Molecular Function | indoleamine 2,3-dioxygenase activity | 294 / 329 | 89.4% | 96.7% of 304 | ≥80% support |
| GO | GO:0034354 Biological Process | 'de novo' NAD biosynthetic process from tryptophan | 294 / 329 | 89.4% | 96.7% of 304 | ≥80% support |
| GO | GO:0004833 Molecular Function | tryptophan 2,3-dioxygenase activity | 278 / 329 | 84.5% | 91.5% of 304 | ≥80% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Cyphastrea salae | ENSOFVP00000033399.1 | XP_020627936.1 | indoleamine 2,3-dioxygenase 2-like [Orbicella faveolata] | Q6ZQW0 Indoleamine 2,3-dioxygenase 2 OS=Homo sapiens OX=9606 GN=IDO | JBrowse |
