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This orthogroup contains 313 genes from 138 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 313 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR22826 | RHO GUANINE EXCHANGE FACTOR-RELATED | 277 / 313 | 88.5% | 100.0% of 277 | ≥80% support |
| GO | GO:0005085 Molecular Function | guanyl-nucleotide exchange factor activity | 277 / 313 | 88.5% | 99.3% of 279 | ≥80% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 277 / 313 | 88.5% | 99.3% of 279 | ≥80% support |
| Pfam | PF00621 | RhoGEF | 244 / 313 | 78.0% | 90.0% of 271 | ≥50% support |
| Pfam | PF00018 | SH3_1 — SH3 domain | 213 / 313 | 68.1% | 78.6% of 271 | ≥50% support |
| Pfam | PF13716 | CRAL_TRIO_2 — Divergent CRAL/TRIO domain | 194 / 313 | 62.0% | 71.6% of 271 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 228 / 313 | 72.8% | 81.7% of 279 | ≥50% support |
| GO | GO:0035556 Biological Process | intracellular signal transduction | 211 / 313 | 67.4% | 75.6% of 279 | ≥50% support |
| KEGG | K20685 | MCF2, ARHGEF14_21_22 — Membrane trafficking | 190 / 313 | 60.7% | 96.9% of 196 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Cyphastrea salae | ENSOFVP00000009171.1 | XP_020603235.1 | guanine nucleotide exchange factor DBS-like [Orbicella faveolata] | Q63406 Guanine nucleotide exchange factor DBS OS=Rattus norvegicus | JBrowse |
| Cyphastrea salae | ENSOFVP00000009184.1 | XP_020603235.1 | guanine nucleotide exchange factor DBS-like [Orbicella faveolata] | Q63406 Guanine nucleotide exchange factor DBS OS=Rattus norvegicus | JBrowse |
