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This orthogroup contains 297 genes from 138 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 297 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11804 | PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED | 274 / 297 | 92.3% | 100.0% of 274 | ≥80% support |
| Pfam | PF01432 | Peptidase_M3 — Peptidase family M3 | 259 / 297 | 87.2% | 99.2% of 261 | ≥80% support |
| GO | GO:0004222 Molecular Function | metalloendopeptidase activity | 274 / 297 | 92.3% | 100.0% of 274 | ≥80% support |
| GO | GO:0006508 Biological Process | proteolysis | 274 / 297 | 92.3% | 100.0% of 274 | ≥80% support |
| GO | GO:0006518 Biological Process | peptide metabolic process | 274 / 297 | 92.3% | 100.0% of 274 | ≥80% support |
| GO | GO:0005758 Cellular Component | mitochondrial intermembrane space | 271 / 297 | 91.3% | 98.9% of 274 | ≥80% support |
| GO | GO:0008237 Molecular Function | metallopeptidase activity | 189 / 297 | 63.6% | 69.0% of 274 | ≥50% support |
| KEGG | K01392 | THOP1 — Peptidases and inhibitors | 177 / 297 | 59.6% | 96.2% of 184 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Cyphastrea salae | ENSOFVP00000012066.1 | CAH3175310.1 | unnamed protein product [Porites lobata] | P47788 Thimet oligopeptidase OS=Sus scrofa OX=9823 GN=THOP1 PE=2 SV | JBrowse |
| Cyphastrea salae | ENSOFVP00000012080.1 | XP_027046737.1 | thimet oligopeptidase-like [Pocillopora damicornis] | P47788 Thimet oligopeptidase OS=Sus scrofa OX=9823 GN=THOP1 PE=2 SV | JBrowse |