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This orthogroup contains 277 genes from 141 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 277 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR46768 | TWO PORE CALCIUM CHANNEL PROTEIN 2 | 241 / 277 | 87.0% | 100.0% of 241 | ≥80% support |
| GO | GO:0005765 Cellular Component | lysosomal membrane | 241 / 277 | 87.0% | 100.0% of 241 | ≥80% support |
| GO | GO:0015280 Molecular Function | ligand-gated sodium channel activity | 241 / 277 | 87.0% | 100.0% of 241 | ≥80% support |
| GO | GO:0019722 Biological Process | calcium-mediated signaling | 241 / 277 | 87.0% | 100.0% of 241 | ≥80% support |
| GO | GO:0022832 Molecular Function | voltage-gated channel activity | 241 / 277 | 87.0% | 100.0% of 241 | ≥80% support |
| GO | GO:0075509 Biological Process | endocytosis involved in viral entry into host cell | 241 / 277 | 87.0% | 100.0% of 241 | ≥80% support |
| GO | GO:0097682 Molecular Function | intracellularly phosphatidylinositol-3,5-bisphosphate-gated monatomic cation channel activity | 241 / 277 | 87.0% | 100.0% of 241 | ≥80% support |
| Pfam | PF00520 | Ion_trans — Ion transport protein | 213 / 277 | 76.9% | 100.0% of 213 | ≥50% support |
| GO | GO:0005216 Molecular Function | monoatomic ion channel activity | 213 / 277 | 76.9% | 88.4% of 241 | ≥50% support |
| GO | GO:0006811 Biological Process | monoatomic ion transport | 213 / 277 | 76.9% | 88.4% of 241 | ≥50% support |
| GO | GO:0016020 Cellular Component | membrane | 213 / 277 | 76.9% | 88.4% of 241 | ≥50% support |
| GO | GO:0055085 Biological Process | transmembrane transport | 213 / 277 | 76.9% | 88.4% of 241 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Cyphastrea salae | ENSOFVP00000019074.1 | XP_020616606.1 | two pore calcium channel protein 2-like [Orbicella faveolata] | A0JMD4 Two pore channel protein 2 OS=Danio rerio OX=7955 GN=tpcn2 P | JBrowse |
| Cyphastrea salae | ENSOFVP00000019085.1 | XP_020616606.1 | two pore calcium channel protein 2-like [Orbicella faveolata] | Q8BWC0 Two pore channel protein 2 OS=Mus musculus OX=10090 GN=Tpcn2 | JBrowse |
| Cyphastrea salae | ENSOFVP00000019102.1 | XP_020616606.1 | two pore calcium channel protein 2-like [Orbicella faveolata] | Q8NHX9 Two pore channel protein 2 OS=Homo sapiens OX=9606 GN=TPCN2 | JBrowse |
