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This orthogroup contains 276 genes from 145 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 276 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11081 | FLAP ENDONUCLEASE FAMILY MEMBER | 238 / 276 | 86.2% | 99.2% of 240 | ≥80% support |
| Pfam | PF00867 | XPG_I — XPG I-region | 224 / 276 | 81.2% | 94.1% of 238 | ≥80% support |
| GO | GO:0004518 Molecular Function | nuclease activity | 238 / 276 | 86.2% | 98.4% of 242 | ≥80% support |
| GO | GO:0017108 Molecular Function | 5'-flap endonuclease activity | 237 / 276 | 85.9% | 97.9% of 242 | ≥80% support |
| GO | GO:0008409 Molecular Function | 5'-3' exonuclease activity | 232 / 276 | 84.1% | 95.9% of 242 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 230 / 276 | 83.3% | 95.0% of 242 | ≥80% support |
| GO | GO:0000287 Molecular Function | magnesium ion binding | 228 / 276 | 82.6% | 94.2% of 242 | ≥80% support |
| GO | GO:0004523 Molecular Function | RNA-DNA hybrid ribonuclease activity | 228 / 276 | 82.6% | 94.2% of 242 | ≥80% support |
| GO | GO:0030145 Molecular Function | manganese ion binding | 228 / 276 | 82.6% | 94.2% of 242 | ≥80% support |
| Pfam | PF00752 | XPG_N — XPG N-terminal domain | 212 / 276 | 76.8% | 89.1% of 238 | ≥50% support |
| GO | GO:0016788 Molecular Function | hydrolase activity, acting on ester bonds | 214 / 276 | 77.5% | 88.4% of 242 | ≥50% support |
| GO | GO:0003677 Molecular Function | DNA binding | 202 / 276 | 73.2% | 83.5% of 242 | ≥50% support |
| GO | GO:0003824 Molecular Function | catalytic activity | 202 / 276 | 73.2% | 83.5% of 242 | ≥50% support |
| KEGG | K04799 | FEN1, RAD2 — Exosome | 191 / 276 | 69.2% | 99.0% of 193 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Cyphastrea salae | ENSOFVP00000003344.1 | XP_020622192.1 | flap endonuclease 1-like [Orbicella faveolata] | A7RRJ0 Flap endonuclease 1 OS=Nematostella vectensis OX=45351 GN=FE | JBrowse |
