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This orthogroup contains 263 genes from 141 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 263 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10133 | DNA POLYMERASE I | 221 / 263 | 84.0% | 96.1% of 230 | ≥80% support |
| GO | GO:0003887 Molecular Function | DNA-directed DNA polymerase activity | 221 / 263 | 84.0% | 96.9% of 228 | ≥80% support |
| GO | GO:0006261 Biological Process | DNA-templated DNA replication | 221 / 263 | 84.0% | 96.9% of 228 | ≥80% support |
| GO | GO:0006302 Biological Process | double-strand break repair | 221 / 263 | 84.0% | 96.9% of 228 | ≥80% support |
| GO | GO:0097681 Biological Process | double-strand break repair via alternative nonhomologous end joining | 221 / 263 | 84.0% | 96.9% of 228 | ≥80% support |
| GO | GO:0003676 Molecular Function | nucleic acid binding | 213 / 263 | 81.0% | 93.4% of 228 | ≥80% support |
| Pfam | PF00270 | DEAD | 189 / 263 | 71.9% | 82.5% of 229 | ≥50% support |
| Pfam | PF21099 | POLQ_helical — DNA_pol_Q helicase like region helical domain | 186 / 263 | 70.7% | 81.2% of 229 | ≥50% support |
| Pfam | PF20470 | HTH_61 — Helix-turn-helix domain | 184 / 263 | 70.0% | 80.4% of 229 | ≥50% support |
| Pfam | PF00476 | DNA_pol_A — DNA polymerase family A | 177 / 263 | 67.3% | 77.3% of 229 | ≥50% support |
| Pfam | PF00271 | Helicase_C — Helicase conserved C-terminal domain | 173 / 263 | 65.8% | 75.6% of 229 | ≥50% support |
| GO | GO:0005524 Molecular Function | ATP binding | 190 / 263 | 72.2% | 83.3% of 228 | ≥50% support |
| GO | GO:0003677 Molecular Function | DNA binding | 177 / 263 | 67.3% | 77.6% of 228 | ≥50% support |
| GO | GO:0006260 Biological Process | DNA replication | 177 / 263 | 67.3% | 77.6% of 228 | ≥50% support |
| KEGG | K02349 | POLQ — DNA repair and recombination proteins | 164 / 263 | 62.4% | 98.8% of 166 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Cyphastrea salae | ENSOFVP00000031201.1 | XP_020623783.1 | LOW QUALITY PROTEIN: uncharacterized protein LOC110061278 [Orbicella faveolata] | O75417 DNA polymerase theta OS=Homo sapiens OX=9606 GN=POLQ PE=1 SV | JBrowse |
| Cyphastrea salae | ENSOFVP00000031214.1 | XP_020623783.1 | LOW QUALITY PROTEIN: uncharacterized protein LOC110061278 [Orbicella faveolata] | O75417 DNA polymerase theta OS=Homo sapiens OX=9606 GN=POLQ PE=1 SV | JBrowse |
