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This orthogroup contains 232 genes from 136 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 232 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR14407 | HERMANSKY-PUDLAK SYNDROME 4 PROTEIN LIGHT-EAR PROTEIN-RELATED | 205 / 232 | 88.4% | 99.5% of 206 | ≥80% support |
| GO | GO:0005085 Molecular Function | guanyl-nucleotide exchange factor activity | 193 / 232 | 83.2% | 97.0% of 199 | ≥80% support |
| GO | GO:0005765 Cellular Component | lysosomal membrane | 193 / 232 | 83.2% | 97.0% of 199 | ≥80% support |
| GO | GO:0006605 Biological Process | protein targeting | 193 / 232 | 83.2% | 97.0% of 199 | ≥80% support |
| GO | GO:0017137 Molecular Function | small GTPase binding | 193 / 232 | 83.2% | 97.0% of 199 | ≥80% support |
| GO | GO:0031085 Cellular Component | BLOC-3 complex | 193 / 232 | 83.2% | 97.0% of 199 | ≥80% support |
| GO | GO:0031410 Cellular Component | cytoplasmic vesicle | 193 / 232 | 83.2% | 97.0% of 199 | ≥80% support |
| GO | GO:1903232 Biological Process | melanosome assembly | 193 / 232 | 83.2% | 97.0% of 199 | ≥80% support |
| Pfam | PF19031 | Intu_longin_1 — First Longin domain of INTU, CCZ1 and HPS4 | 154 / 232 | 66.4% | 90.6% of 170 | ≥50% support |
| GO | GO:0016192 Biological Process | vesicle-mediated transport | 169 / 232 | 72.8% | 84.9% of 199 | ≥50% support |
| KEGG | K20194 | HPS4 — Membrane trafficking | 133 / 232 | 57.3% | 97.8% of 136 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Cyphastrea salae | ENSOFVP00000011065.1 | XP_020613749.1 | uncharacterized protein LOC110051974 [Orbicella faveolata] | – | JBrowse |
| Cyphastrea salae | ENSOFVP00000014676.1 | KAJ7387366.1 | melanosome assembly [Desmophyllum pertusum] | – | JBrowse |