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This orthogroup contains 224 genes from 140 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 224 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR45679 | ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2 | 204 / 224 | 91.1% | 100.0% of 204 | ≥80% support |
| Pfam | PF01532 | Glyco_hydro_47 — Glycosyl hydrolase family 47 | 204 / 224 | 91.1% | 100.0% of 204 | ≥80% support |
| GO | GO:0004571 Molecular Function | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity | 204 / 224 | 91.1% | 100.0% of 204 | ≥80% support |
| GO | GO:0005509 Molecular Function | calcium ion binding | 204 / 224 | 91.1% | 100.0% of 204 | ≥80% support |
| GO | GO:0005783 Cellular Component | endoplasmic reticulum | 204 / 224 | 91.1% | 100.0% of 204 | ≥80% support |
| GO | GO:0005975 Biological Process | carbohydrate metabolic process | 204 / 224 | 91.1% | 100.0% of 204 | ≥80% support |
| GO | GO:0016020 Cellular Component | membrane | 204 / 224 | 91.1% | 100.0% of 204 | ≥80% support |
| GO | GO:1904380 Biological Process | endoplasmic reticulum mannose trimming | 204 / 224 | 91.1% | 100.0% of 204 | ≥80% support |
| GO | GO:1904382 Biological Process | mannose trimming involved in glycoprotein ERAD pathway | 204 / 224 | 91.1% | 100.0% of 204 | ≥80% support |
| KEGG | K10085 | EDEM2 — Lectins | 160 / 224 | 71.4% | 100.0% of 160 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Cyphastrea salae | ENSOFVP00000002668.1 | XP_020615082.1 | ER degradation-enhancing alpha-mannosidase-like protein 2 isoform X1 [Orbicella faveolata] | Q8BJT9 ER degradation-enhancing alpha-mannosidase-like protein 2 OS | JBrowse |
| Cyphastrea salae | ENSOFVP00000002680.1 | XP_020615082.1 | ER degradation-enhancing alpha-mannosidase-like protein 2 isoform X1 [Orbicella faveolata] | Q9BV94 ER degradation-enhancing alpha-mannosidase-like protein 2 OS | JBrowse |
| Cyphastrea salae | ENSOFVP00000002690.1 | XP_020615082.1 | ER degradation-enhancing alpha-mannosidase-like protein 2 isoform X1 [Orbicella faveolata] | Q9BV94 ER degradation-enhancing alpha-mannosidase-like protein 2 OS | JBrowse |