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This orthogroup contains 214 genes from 112 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 214 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11409 | ADENOSINE DEAMINASE | 198 / 214 | 92.5% | 97.5% of 203 | ≥80% support |
| Pfam | PF00962 | A_deaminase — Adenosine deaminase | 203 / 214 | 94.9% | 100.0% of 203 | ≥80% support |
| GO | GO:0019239 Molecular Function | deaminase activity | 203 / 214 | 94.9% | 100.0% of 203 | ≥80% support |
| GO | GO:0005829 Cellular Component | cytosol | 201 / 214 | 93.9% | 99.0% of 203 | ≥80% support |
| GO | GO:0043103 Biological Process | hypoxanthine salvage | 201 / 214 | 93.9% | 99.0% of 203 | ≥80% support |
| GO | GO:0004000 Molecular Function | adenosine deaminase activity | 198 / 214 | 92.5% | 97.5% of 203 | ≥80% support |
| GO | GO:0006154 Biological Process | adenosine catabolic process | 198 / 214 | 92.5% | 97.5% of 203 | ≥80% support |
| GO | GO:0046103 Biological Process | inosine biosynthetic process | 198 / 214 | 92.5% | 97.5% of 203 | ≥80% support |
| GO | GO:0009897 Cellular Component | external side of plasma membrane | 193 / 214 | 90.2% | 95.1% of 203 | ≥80% support |
| GO | GO:0060169 Biological Process | negative regulation of adenosine receptor signaling pathway | 193 / 214 | 90.2% | 95.1% of 203 | ≥80% support |
| GO | GO:0009168 Biological Process | purine ribonucleoside monophosphate biosynthetic process | 152 / 214 | 71.0% | 74.9% of 203 | ≥50% support |
| KEGG | K01488 | add, ADA — Primary immunodeficiency | 149 / 214 | 69.6% | 98.0% of 152 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Cyphastrea salae | ENSOFVP00000031990.1 | XP_020610606.1 | adenosine deaminase-like isoform X2 [Orbicella faveolata] | Q63ZU0 Adenosine deaminase OS=Xenopus tropicalis OX=8364 GN=ada PE= | JBrowse |
| Cyphastrea salae | ENSOFVP00000032001.1 | XP_020610606.1 | adenosine deaminase-like isoform X2 [Orbicella faveolata] | Q63ZU0 Adenosine deaminase OS=Xenopus tropicalis OX=8364 GN=ada PE= | JBrowse |
