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This orthogroup contains 182 genes from 138 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 182 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR13113 | ECSIT EVOLUTIONARILY CONSERVED SIGNALING INTERMEDIATE IN TOLL PATHWAYS | 158 / 182 | 86.8% | 99.4% of 159 | ≥80% support |
| Pfam | PF06239 | ECSIT_N — Evolutionarily conserved signalling intermediate in Toll pathway | 155 / 182 | 85.2% | 97.5% of 159 | ≥80% support |
| GO | GO:0005739 Cellular Component | mitochondrion | 159 / 182 | 87.4% | 100.0% of 159 | ≥80% support |
| GO | GO:0007178 Biological Process | cell surface receptor protein serine/threonine kinase signaling pathway | 158 / 182 | 86.8% | 99.4% of 159 | ≥80% support |
| GO | GO:0045087 Biological Process | innate immune response | 158 / 182 | 86.8% | 99.4% of 159 | ≥80% support |
| Pfam | PF14784 | ECSIT_C — C-terminal domain of the ECSIT protein | 137 / 182 | 75.3% | 86.2% of 159 | ≥50% support |
| KEGG | K04405 | ECSIT — Mitochondrial biogenesis | 120 / 182 | 65.9% | 99.2% of 121 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Cyphastrea salae | ENSOFVP00000033613.1 | XP_020628008.1 | evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial-like [Orbicella faveolata] | Q08CK1 Evolutionarily conserved signaling intermediate in Toll path | JBrowse |
