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This orthogroup contains 176 genes from 120 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 176 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR21445 | ENDONUCLEASE IV ENDODEOXYRIBONUCLEASE IV | 162 / 176 | 92.1% | 100.0% of 162 | ≥80% support |
| Pfam | PF01261 | AP_endonuc_2 — Xylose isomerase-like TIM barrel | 161 / 176 | 91.5% | 100.0% of 161 | ≥80% support |
| GO | GO:0003677 Molecular Function | DNA binding | 162 / 176 | 92.1% | 100.0% of 162 | ≥80% support |
| GO | GO:0003906 Molecular Function | DNA-(apurinic or apyrimidinic site) endonuclease activity | 162 / 176 | 92.1% | 100.0% of 162 | ≥80% support |
| GO | GO:0006281 Biological Process | DNA repair | 162 / 176 | 92.1% | 100.0% of 162 | ≥80% support |
| GO | GO:0006284 Biological Process | base-excision repair | 162 / 176 | 92.1% | 100.0% of 162 | ≥80% support |
| GO | GO:0008081 Molecular Function | phosphoric diester hydrolase activity | 162 / 176 | 92.1% | 100.0% of 162 | ≥80% support |
| GO | GO:0008270 Molecular Function | zinc ion binding | 162 / 176 | 92.1% | 100.0% of 162 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 153 / 176 | 86.9% | 94.4% of 162 | ≥80% support |
| GO | GO:0005739 Cellular Component | mitochondrion | 153 / 176 | 86.9% | 94.4% of 162 | ≥80% support |
| KEGG | K10771 | APEX1 — DNA repair and recombination proteins | 100 / 176 | 56.8% | 90.1% of 111 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Cyphastrea salae | ENSOFVP00000036888.1 | XP_020626573.1 | uncharacterized protein LOC110063919 [Orbicella faveolata] | Q8IE02 Apurinic-apyrimidinic endonuclease 1 OS=Plasmodium falciparu | JBrowse |
