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This orthogroup contains 153 genes from 108 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 153 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10985 | BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED | 136 / 153 | 88.9% | 100.0% of 136 | ≥80% support |
| Pfam | PF00010 | HLH — Helix-loop-helix DNA-binding domain | 133 / 153 | 86.9% | 97.1% of 137 | ≥80% support |
| GO | GO:0000978 Molecular Function | RNA polymerase II cis-regulatory region sequence-specific DNA binding | 136 / 153 | 88.9% | 98.6% of 138 | ≥80% support |
| GO | GO:0000981 Molecular Function | DNA-binding transcription factor activity, RNA polymerase II-specific | 136 / 153 | 88.9% | 98.6% of 138 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 136 / 153 | 88.9% | 98.6% of 138 | ≥80% support |
| GO | GO:0006357 Biological Process | regulation of transcription by RNA polymerase II | 136 / 153 | 88.9% | 98.6% of 138 | ≥80% support |
| GO | GO:0046983 Molecular Function | protein dimerization activity | 136 / 153 | 88.9% | 98.6% of 138 | ≥80% support |
| GO | GO:0009952 Biological Process | anterior/posterior pattern specification | 133 / 153 | 86.9% | 96.4% of 138 | ≥80% support |
| GO | GO:0050767 Biological Process | regulation of neurogenesis | 133 / 153 | 86.9% | 96.4% of 138 | ≥80% support |
| GO | GO:0003677 Molecular Function | DNA binding | 127 / 153 | 83.0% | 92.0% of 138 | ≥80% support |
| GO | GO:0006355 Biological Process | regulation of DNA-templated transcription | 127 / 153 | 83.0% | 92.0% of 138 | ≥80% support |
| Pfam | PF07527 | Hairy_orange — Hairy Orange | 115 / 153 | 75.2% | 83.9% of 137 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Cyphastrea salae | ENSOFVP00000016936.1 | XP_020616536.1 | transcription factor cwo-like isoform X2 [Orbicella faveolata] | Q7KM13 Hairy/enhancer-of-split related with YRPW motif protein OS=D | JBrowse |
| Cyphastrea salae | ENSOFVP00000016943.1 | XP_020616535.1 | class E basic helix-loop-helix protein 40-like isoform X1 [Orbicella faveolata] | Q7KM13 Hairy/enhancer-of-split related with YRPW motif protein OS=D | JBrowse |
