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Support counts the member genes carrying the term. % of genes is that count over all 430 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11822 | NADP-SPECIFIC ISOCITRATE DEHYDROGENASE | 386 / 430 | 89.8% | 99.7% of 387 | ≥80% support |
| Pfam | PF00180 | Iso_dh — Isocitrate/isopropylmalate dehydrogenase | 383 / 430 | 89.1% | 99.7% of 384 | ≥80% support |
| GO | GO:0004450 Molecular Function | isocitrate dehydrogenase (NADP+) activity | 386 / 430 | 89.8% | 100.0% of 386 | ≥80% support |
| GO | GO:0006102 Biological Process | isocitrate metabolic process | 386 / 430 | 89.8% | 100.0% of 386 | ≥80% support |
| GO | GO:0005739 Cellular Component | mitochondrion | 365 / 430 | 84.9% | 94.6% of 386 | ≥80% support |
| GO | GO:0006739 Biological Process | NADP metabolic process | 365 / 430 | 84.9% | 94.6% of 386 | ≥80% support |
| GO | GO:0000287 Molecular Function | magnesium ion binding | 334 / 430 | 77.7% | 86.5% of 386 | ≥50% support |
| GO | GO:0016616 Molecular Function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | 334 / 430 | 77.7% | 86.5% of 386 | ≥50% support |
| GO | GO:0051287 Molecular Function | NAD binding | 334 / 430 | 77.7% | 86.5% of 386 | ≥50% support |
| GO | GO:0005777 Cellular Component | peroxisome | 328 / 430 | 76.3% | 85.0% of 386 | ≥50% support |
| GO | GO:0005829 Cellular Component | cytosol | 328 / 430 | 76.3% | 85.0% of 386 | ≥50% support |
| KEGG | K00031 | IDH1, IDH2, icd — Central carbon metabolism in cancer | 315 / 430 | 73.3% | 99.4% of 317 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Dendronephthya gigantea | XP_028393930.1 | XP_028393930.1 | isocitrate dehydrogenase [NADP] cytoplasmic-like [Dendronephthya gigantea] | O75874 Isocitrate dehydrogenase [NADP] cytoplasmic OS=Homo sapiens | JBrowse |
| Dendronephthya gigantea | XP_028399162.1 | XP_028399162.1 | isocitrate dehydrogenase [NADP]-like [Dendronephthya gigantea] | P54071 Isocitrate dehydrogenase [NADP], mitochondrial OS=Mus muscul | JBrowse |
