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This orthogroup contains 3,972 genes from 149 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 3,972 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11733 | ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED | 3597 / 3,972 | 90.6% | 99.8% of 3,605 | ≥80% support |
| Pfam | PF05649 | Peptidase_M13_N — Peptidase family M13 | 3359 / 3,972 | 84.6% | 91.9% of 3,656 | ≥80% support |
| GO | GO:0006508 Biological Process | proteolysis | 3664 / 3,972 | 92.3% | 100.0% of 3,666 | ≥80% support |
| GO | GO:0004222 Molecular Function | metalloendopeptidase activity | 3627 / 3,972 | 91.3% | 98.9% of 3,666 | ≥80% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 3598 / 3,972 | 90.6% | 98.2% of 3,666 | ≥80% support |
| GO | GO:0016485 Biological Process | protein processing | 3574 / 3,972 | 90.0% | 97.5% of 3,666 | ≥80% support |
| GO | GO:0008237 Molecular Function | metallopeptidase activity | 3515 / 3,972 | 88.5% | 95.9% of 3,666 | ≥80% support |
| Pfam | PF01431 | Peptidase_M13 — Peptidase family M13 | 3117 / 3,972 | 78.5% | 85.3% of 3,656 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Desmophyllum pertusum | KAJ7331607.1 | KAJ7331607.1 | hypothetical protein OS493_019192 [Desmophyllum pertusum] | P97739 Endothelin-converting enzyme 1 OS=Cavia porcellus OX=10141 G | JBrowse |
| Desmophyllum pertusum | KAJ7331609.1 | KAJ7331609.1 | hypothetical protein OS493_019194 [Desmophyllum pertusum] | P97739 Endothelin-converting enzyme 1 OS=Cavia porcellus OX=10141 G | JBrowse |
| Desmophyllum pertusum | KAJ7333074.1 | KAJ7333074.1 | hypothetical protein OS493_018244 [Desmophyllum pertusum] | Q8IS64 Endothelin-converting enzyme homolog OS=Locusta migratoria O | JBrowse |
| Desmophyllum pertusum | KAJ7354731.1 | KAJ7354731.1 | hypothetical protein OS493_030507 [Desmophyllum pertusum] | Q8IS64 Endothelin-converting enzyme homolog OS=Locusta migratoria O | JBrowse |
| Desmophyllum pertusum | KAJ7354732.1 | KAJ7354732.1 | hypothetical protein OS493_030508 [Desmophyllum pertusum] | F1N476 Endothelin-converting enzyme 2 OS=Bos taurus OX=9913 GN=ECE2 | JBrowse |
| Desmophyllum pertusum | KAJ7370169.1 | KAJ7370169.1 | hypothetical protein OS493_033794 [Desmophyllum pertusum] | O44857 Neprilysin-2 OS=Caenorhabditis elegans OX=6239 GN=nep-2 PE=1 | JBrowse |
| Desmophyllum pertusum | KAJ7373659.1 | KAJ7373659.1 | hypothetical protein OS493_011268 [Desmophyllum pertusum] | P42893 Endothelin-converting enzyme 1 OS=Rattus norvegicus OX=10116 | JBrowse |
| Desmophyllum pertusum | KAJ7373661.1 | KAJ7373661.1 | hypothetical protein OS493_011270 [Desmophyllum pertusum] | Q9JLI3 Membrane metallo-endopeptidase-like 1 OS=Mus musculus OX=100 | JBrowse |
| Desmophyllum pertusum | KAJ7373662.1 | KAJ7373662.1 | hypothetical protein OS493_011271 [Desmophyllum pertusum] | O44857 Neprilysin-2 OS=Caenorhabditis elegans OX=6239 GN=nep-2 PE=1 | JBrowse |
| Desmophyllum pertusum | KAJ7377080.1 | KAJ7377080.1 | Membrane metallo-endopeptidase-like 1 [Desmophyllum pertusum] | Q9W436 Neprilysin-1 OS=Drosophila melanogaster OX=7227 GN=Nep1 PE=2 | JBrowse |
| Desmophyllum pertusum | KAJ7377081.1 | KAJ7377081.1 | hypothetical protein OS493_030675 [Desmophyllum pertusum] | P42893 Endothelin-converting enzyme 1 OS=Rattus norvegicus OX=10116 | JBrowse |
| Desmophyllum pertusum | KAJ7377717.1 | KAJ7377717.1 | hypothetical protein OS493_027279 [Desmophyllum pertusum] | Q4PZA2 Endothelin-converting enzyme 1 OS=Mus musculus OX=10090 GN=E | JBrowse |
| Desmophyllum pertusum | KAJ7377718.1 | KAJ7377718.1 | hypothetical protein OS493_027280 [Desmophyllum pertusum] | P97739 Endothelin-converting enzyme 1 OS=Cavia porcellus OX=10141 G | JBrowse |
| Desmophyllum pertusum | KAJ7379474.1 | KAJ7379474.1 | hypothetical protein OS493_015257 [Desmophyllum pertusum] | Q8IS64 Endothelin-converting enzyme homolog OS=Locusta migratoria O | JBrowse |
| Desmophyllum pertusum | KAJ7382376.1 | KAJ7382376.1 | hypothetical protein OS493_035437 [Desmophyllum pertusum] | B2RQR8 Endothelin-converting enzyme 2 OS=Mus musculus OX=10090 GN=E | JBrowse |
| Desmophyllum pertusum | KAJ7393276.1 | KAJ7393276.1 | Endothelin-converting enzyme 1 [Desmophyllum pertusum] | Q8IS64 Endothelin-converting enzyme homolog OS=Locusta migratoria O | JBrowse |
| Desmophyllum pertusum | KAJ7393277.1 | KAJ7393277.1 | Metalloendopeptidase [Desmophyllum pertusum] | B2RQR8 Endothelin-converting enzyme 2 OS=Mus musculus OX=10090 GN=E | JBrowse |
| Desmophyllum pertusum | KAJ7393583.1 | KAJ7393583.1 | Endothelin-converting enzyme 2 [Desmophyllum pertusum] | Q8IS64 Endothelin-converting enzyme homolog OS=Locusta migratoria O | JBrowse |
| Desmophyllum pertusum | KAJ7393920.1 | KAJ7393920.1 | Endothelin-converting enzyme 2 [Desmophyllum pertusum] | Q8IS64 Endothelin-converting enzyme homolog OS=Locusta migratoria O | JBrowse |
| Desmophyllum pertusum | KAJ7393921.1 | KAJ7393921.1 | hypothetical protein OS493_003590 [Desmophyllum pertusum] | P42893 Endothelin-converting enzyme 1 OS=Rattus norvegicus OX=10116 | JBrowse |