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This orthogroup contains 717 genes from 146 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 717 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| GO | GO:0005737 Cellular Component | cytoplasm | 605 / 717 | 84.4% | 93.7% of 646 | ≥80% support |
| PANTHER | PTHR14950 | DICER-RELATED | 573 / 717 | 79.9% | 90.2% of 635 | ≥50% support |
| Pfam | PF00636 | Ribonuclease_3 — Ribonuclease III domain | 520 / 717 | 72.5% | 80.6% of 645 | ≥50% support |
| Pfam | PF03368 | Dicer_dimer — Dicer dimerisation domain | 451 / 717 | 62.9% | 69.9% of 645 | ≥50% support |
| Pfam | PF20932 | Dicer_dsRBD — Dicer, dsRNA-binding domain | 445 / 717 | 62.1% | 69.0% of 645 | ≥50% support |
| Pfam | PF02170 | PAZ | 416 / 717 | 58.0% | 64.5% of 645 | ≥50% support |
| Pfam | PF20931 | Dicer_platform — Dicer, platform domain | 383 / 717 | 53.4% | 59.4% of 645 | ≥50% support |
| GO | GO:0004525 Molecular Function | ribonuclease III activity | 567 / 717 | 79.1% | 87.8% of 646 | ≥50% support |
| GO | GO:0003723 Molecular Function | RNA binding | 564 / 717 | 78.7% | 87.3% of 646 | ≥50% support |
| GO | GO:0030422 Biological Process | siRNA processing | 557 / 717 | 77.7% | 86.2% of 646 | ≥50% support |
| GO | GO:0016442 Cellular Component | RISC complex | 547 / 717 | 76.3% | 84.7% of 646 | ≥50% support |
| GO | GO:0090501 Biological Process | obsolete RNA phosphodiester bond hydrolysis | 547 / 717 | 76.3% | 84.7% of 646 | ≥50% support |
| GO | GO:0005634 Cellular Component | nucleus | 547 / 717 | 76.3% | 84.7% of 646 | ≥50% support |
| GO | GO:0006396 Biological Process | RNA processing | 541 / 717 | 75.5% | 83.8% of 646 | ≥50% support |
| GO | GO:0031054 Biological Process | pre-miRNA processing | 538 / 717 | 75.0% | 83.3% of 646 | ≥50% support |
| GO | GO:0006309 Biological Process | apoptotic DNA fragmentation | 481 / 717 | 67.1% | 74.5% of 646 | ≥50% support |
| GO | GO:0004530 Molecular Function | deoxyribonuclease I activity | 481 / 717 | 67.1% | 74.5% of 646 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 462 / 717 | 64.4% | 71.5% of 646 | ≥50% support |
| GO | GO:0016891 Molecular Function | RNA endonuclease activity, producing 5'-phosphomonoesters | 458 / 717 | 63.9% | 70.9% of 646 | ≥50% support |
| KEGG | K11592 | DICER1, DCR1 — Chromosome and associated proteins | 373 / 717 | 52.0% | 97.1% of 384 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Desmophyllum pertusum | KAJ7376506.1 | KAJ7376506.1 | Endoribonuclease Dicer [Desmophyllum pertusum] | Q6TV19 Endoribonuclease Dicer OS=Danio rerio OX=7955 GN=dicer1 PE=2 | JBrowse |
| Desmophyllum pertusum | KAJ7376507.1 | KAJ7376507.1 | Endoribonuclease Dicer [Desmophyllum pertusum] | A0A974H8H3 Endoribonuclease Dicer-L OS=Xenopus laevis OX=8355 GN=dicer1 | JBrowse |
| Desmophyllum pertusum | KAJ7383935.1 | KAJ7383935.1 | Endoribonuclease Dicer [Desmophyllum pertusum] | Q6TV19 Endoribonuclease Dicer OS=Danio rerio OX=7955 GN=dicer1 PE=2 | JBrowse |
| Desmophyllum pertusum | KAJ7383936.1 | KAJ7383936.1 | hypothetical protein OS493_024621 [Desmophyllum pertusum] | Q6TV19 Endoribonuclease Dicer OS=Danio rerio OX=7955 GN=dicer1 PE=2 | JBrowse |
| Desmophyllum pertusum | KAJ7383941.1 | KAJ7383941.1 | Endoribonuclease Dicer [Desmophyllum pertusum] | Q6TUI4 Endoribonuclease Dicer OS=Bos taurus OX=9913 GN=DICER1 PE=2 | JBrowse |
| Desmophyllum pertusum | KAJ7383942.1 | KAJ7383942.1 | Endoribonuclease Dicer [Desmophyllum pertusum] | Q9VCU9 Endoribonuclease Dcr-1 OS=Drosophila melanogaster OX=7227 GN | JBrowse |
| Desmophyllum pertusum | KAJ7383943.1 | KAJ7383943.1 | hypothetical protein OS493_024628 [Desmophyllum pertusum] | B3DLA6 Endoribonuclease Dicer OS=Xenopus tropicalis OX=8364 GN=dice | JBrowse |
