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This orthogroup contains 682 genes from 143 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 682 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10625 | HISTONE DEACETYLASE HDAC1-RELATED | 528 / 682 | 77.4% | 95.8% of 551 | ≥50% support |
| Pfam | PF00850 | Hist_deacetyl — Histone deacetylase domain | 531 / 682 | 77.9% | 99.3% of 535 | ≥50% support |
| GO | GO:0004407 Molecular Function | histone deacetylase activity | 526 / 682 | 77.1% | 98.7% of 533 | ≥50% support |
| GO | GO:0016575 Biological Process | obsolete histone deacetylation | 526 / 682 | 77.1% | 98.7% of 533 | ≥50% support |
| GO | GO:0000122 Biological Process | negative regulation of transcription by RNA polymerase II | 522 / 682 | 76.5% | 97.9% of 533 | ≥50% support |
| GO | GO:0008134 Molecular Function | transcription factor binding | 521 / 682 | 76.4% | 97.8% of 533 | ≥50% support |
| GO | GO:0000118 Cellular Component | histone deacetylase complex | 500 / 682 | 73.3% | 93.8% of 533 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Desmophyllum pertusum | KAJ7369596.1 | KAJ7369596.1 | polyubiquitinated misfolded protein transport [Desmophyllum pertusum] | A0A8I6GM68 Protein deacetylase HDAC6 OS=Rattus norvegicus OX=10116 GN=H | JBrowse |
| Desmophyllum pertusum | KAJ7380225.1 | KAJ7380225.1 | Histone deacetylase 7 [Desmophyllum pertusum] | P83038 Histone deacetylase 4 OS=Gallus gallus OX=9031 GN=HDAC4 PE=2 | JBrowse |
