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This orthogroup contains 517 genes from 146 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 517 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR43655 | ATP-DEPENDENT PROTEASE | 415 / 517 | 80.3% | 92.6% of 448 | ≥80% support |
| GO | GO:0005524 Molecular Function | ATP binding | 452 / 517 | 87.4% | 99.8% of 453 | ≥80% support |
| GO | GO:0004222 Molecular Function | metalloendopeptidase activity | 449 / 517 | 86.9% | 99.1% of 453 | ≥80% support |
| GO | GO:0004176 Molecular Function | ATP-dependent peptidase activity | 438 / 517 | 84.7% | 96.7% of 453 | ≥80% support |
| Pfam | PF00004 | AAA | 403 / 517 | 78.0% | 89.0% of 453 | ≥50% support |
| Pfam | PF01434 | Peptidase_M41 — Peptidase family M41 | 401 / 517 | 77.6% | 88.5% of 453 | ≥50% support |
| Pfam | PF17862 | AAA_lid_3 — AAA+ lid domain | 379 / 517 | 73.3% | 83.7% of 453 | ≥50% support |
| Pfam | PF06480 | FtsH_ext — FtsH Extracellular | 311 / 517 | 60.2% | 68.7% of 453 | ≥50% support |
| GO | GO:0005745 Cellular Component | m-AAA complex | 409 / 517 | 79.1% | 90.3% of 453 | ≥50% support |
| GO | GO:0034982 Biological Process | mitochondrial protein processing | 409 / 517 | 79.1% | 90.3% of 453 | ≥50% support |
| GO | GO:0006508 Biological Process | proteolysis | 406 / 517 | 78.5% | 89.6% of 453 | ≥50% support |
| GO | GO:0016887 Molecular Function | ATP hydrolysis activity | 403 / 517 | 78.0% | 89.0% of 453 | ≥50% support |
| GO | GO:0016020 Cellular Component | membrane | 365 / 517 | 70.6% | 80.6% of 453 | ≥50% support |
| GO | GO:0008270 Molecular Function | zinc ion binding | 311 / 517 | 60.2% | 68.7% of 453 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Desmophyllum pertusum | KAJ7351145.1 | KAJ7351145.1 | Paraplegin [Desmophyllum pertusum] | Q9UQ90 Mitochondrial inner membrane m-AAA protease component parapl | JBrowse |
| Desmophyllum pertusum | KAJ7351146.1 | KAJ7351146.1 | Paraplegin [Desmophyllum pertusum] | Q9UQ90 Mitochondrial inner membrane m-AAA protease component parapl | JBrowse |
| Desmophyllum pertusum | KAJ7351147.1 | KAJ7351147.1 | Paraplegin [Desmophyllum pertusum] | – | JBrowse |
| Desmophyllum pertusum | KAJ7351155.1 | KAJ7351155.1 | Paraplegin [Desmophyllum pertusum] | Q3ULF4 Mitochondrial inner membrane m-AAA protease component parapl | JBrowse |
| Desmophyllum pertusum | KAJ7351156.1 | KAJ7351156.1 | Paraplegin [Desmophyllum pertusum] | Q9UQ90 Mitochondrial inner membrane m-AAA protease component parapl | JBrowse |
| Desmophyllum pertusum | KAJ7374721.1 | KAJ7374721.1 | AFG3-like protein 2 [Desmophyllum pertusum] | Q9Y4W6 Mitochondrial inner membrane m-AAA protease component AFG3L2 | JBrowse |
| Desmophyllum pertusum | KAJ7374722.1 | KAJ7374722.1 | AFG3-like protein 2 [Desmophyllum pertusum] | Q9HGM3 Mitochondrial inner membrane m-AAA protease component yta12 | JBrowse |
