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This orthogroup contains 496 genes from 101 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 496 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| Pfam | PF00001 | 7tm_1 — 7 transmembrane receptor (rhodopsin family) | 476 / 496 | 96.0% | 100.0% of 476 | ≥80% support |
| GO | GO:0004930 Molecular Function | G protein-coupled receptor activity | 476 / 496 | 96.0% | 100.0% of 476 | ≥80% support |
| GO | GO:0007186 Biological Process | G protein-coupled receptor signaling pathway | 476 / 496 | 96.0% | 100.0% of 476 | ≥80% support |
| GO | GO:0016020 Cellular Component | membrane | 476 / 496 | 96.0% | 100.0% of 476 | ≥80% support |
| PANTHER | PTHR24247 | 5-HYDROXYTRYPTAMINE RECEPTOR | 349 / 496 | 70.4% | 73.5% of 475 | ≥50% support |
| GO | GO:0005887 Cellular Component | plasma membrane | 377 / 496 | 76.0% | 79.2% of 476 | ≥50% support |
| GO | GO:0004993 Molecular Function | G protein-coupled serotonin receptor activity | 349 / 496 | 70.4% | 73.3% of 476 | ≥50% support |
| GO | GO:0007187 Biological Process | G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | 349 / 496 | 70.4% | 73.3% of 476 | ≥50% support |
| GO | GO:0007268 Biological Process | chemical synaptic transmission | 349 / 496 | 70.4% | 73.3% of 476 | ≥50% support |
| GO | GO:0030425 Cellular Component | dendrite | 349 / 496 | 70.4% | 73.3% of 476 | ≥50% support |
| GO | GO:0030594 Molecular Function | neurotransmitter receptor activity | 349 / 496 | 70.4% | 73.3% of 476 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Desmophyllum pertusum | KAJ7321190.1 | KAJ7321190.1 | hypothetical protein OS493_035368 [Desmophyllum pertusum] | Q8JG69 Alpha-2Db adrenergic receptor OS=Danio rerio OX=7955 GN=adra | JBrowse |
| Desmophyllum pertusum | KAJ7328124.1 | KAJ7328124.1 | hypothetical protein OS493_025524, partial [Desmophyllum pertusum] | P47747 Histamine H2 receptor OS=Cavia porcellus OX=10141 GN=HRH2 PE | JBrowse |
| Desmophyllum pertusum | KAJ7360415.1 | KAJ7360415.1 | hypothetical protein OS493_015515 [Desmophyllum pertusum] | Q61224 5-hydroxytryptamine receptor 1D OS=Mus musculus OX=10090 GN= | JBrowse |
| Desmophyllum pertusum | KAJ7363405.1 | KAJ7363405.1 | Histamine H2 receptor [Desmophyllum pertusum] | P49145 5-hydroxytryptamine receptor 1D OS=Oryctolagus cuniculus OX= | JBrowse |
| Desmophyllum pertusum | KAJ7391722.1 | KAJ7391722.1 | Histamine H2 receptor [Desmophyllum pertusum] | P50130 D(1A) dopamine receptor OS=Sus scrofa OX=9823 GN=DRD1 PE=3 S | JBrowse |
| Desmophyllum pertusum | KAJ7393234.1 | KAJ7393234.1 | hypothetical protein OS493_006203 [Desmophyllum pertusum] | P34969 5-hydroxytryptamine receptor 7 OS=Homo sapiens OX=9606 GN=HT | JBrowse |
