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This orthogroup contains 419 genes from 142 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 419 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR12411 | CYSTEINE PROTEASE FAMILY C1-RELATED | 347 / 419 | 82.8% | 99.4% of 349 | ≥80% support |
| Pfam | PF00112 | Peptidase_C1 — Papain family cysteine protease | 360 / 419 | 85.9% | 100.0% of 360 | ≥80% support |
| GO | GO:0006508 Biological Process | proteolysis | 360 / 419 | 85.9% | 100.0% of 360 | ≥80% support |
| GO | GO:0008234 Molecular Function | cysteine-type peptidase activity | 360 / 419 | 85.9% | 100.0% of 360 | ≥80% support |
| GO | GO:0004197 Molecular Function | cysteine-type endopeptidase activity | 347 / 419 | 82.8% | 96.4% of 360 | ≥80% support |
| GO | GO:0005615 Cellular Component | extracellular space | 347 / 419 | 82.8% | 96.4% of 360 | ≥80% support |
| GO | GO:0005764 Cellular Component | lysosome | 347 / 419 | 82.8% | 96.4% of 360 | ≥80% support |
| GO | GO:0051603 Biological Process | proteolysis involved in protein catabolic process | 347 / 419 | 82.8% | 96.4% of 360 | ≥80% support |
| KEGG | K01363 | CTSB — Glycosaminoglycan binding proteins | 217 / 419 | 51.8% | 99.5% of 218 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Desmophyllum pertusum | KAJ7360178.1 | KAJ7360178.1 | hypothetical protein OS493_018170 [Desmophyllum pertusum] | Q4R5M2 Cathepsin B OS=Macaca fascicularis OX=9541 GN=CTSB PE=2 SV=1 | JBrowse |
| Desmophyllum pertusum | KAJ7360179.1 | KAJ7360179.1 | hypothetical protein OS493_018171 [Desmophyllum pertusum] | P43508 Cathepsin B-like cysteine proteinase 4 OS=Caenorhabditis ele | JBrowse |
| Desmophyllum pertusum | KAJ7360180.1 | KAJ7360180.1 | hypothetical protein OS493_018172 [Desmophyllum pertusum] | – | JBrowse |
| Desmophyllum pertusum | KAJ7370099.1 | KAJ7370099.1 | hypothetical protein OS493_034310 [Desmophyllum pertusum] | P10605 Cathepsin B OS=Mus musculus OX=10090 GN=Ctsb PE=1 SV=2 | JBrowse |
| Desmophyllum pertusum | KAJ7370100.1 | KAJ7370100.1 | hypothetical protein OS493_034311 [Desmophyllum pertusum] | P83205 Cathepsin B OS=Ovis aries OX=9940 GN=CTSB PE=1 SV=2 | JBrowse |