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This orthogroup contains 339 genes from 141 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 339 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11254 | HECT DOMAIN UBIQUITIN-PROTEIN LIGASE | 266 / 339 | 78.5% | 98.9% of 269 | ≥50% support |
| Pfam | PF00632 | HECT | 264 / 339 | 77.9% | 95.0% of 278 | ≥50% support |
| GO | GO:0004842 Molecular Function | ubiquitin-protein transferase activity | 271 / 339 | 79.9% | 99.6% of 272 | ≥50% support |
| GO | GO:0000209 Biological Process | protein polyubiquitination | 267 / 339 | 78.8% | 98.2% of 272 | ≥50% support |
| GO | GO:0061630 Molecular Function | ubiquitin protein ligase activity | 267 / 339 | 78.8% | 98.2% of 272 | ≥50% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 266 / 339 | 78.5% | 97.8% of 272 | ≥50% support |
| GO | GO:0016567 Biological Process | protein ubiquitination | 266 / 339 | 78.5% | 97.8% of 272 | ≥50% support |
| GO | GO:0043066 Biological Process | negative regulation of apoptotic process | 266 / 339 | 78.5% | 97.8% of 272 | ≥50% support |
| KEGG | K22370 | AREL1 — Ubiquitin system | 196 / 339 | 57.8% | 95.6% of 205 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Desmophyllum pertusum | KAJ7365476.1 | KAJ7365476.1 | Apoptosis-resistant E3 ubiquitin protein ligase 1 [Desmophyllum pertusum] | O15033 Apoptosis-resistant E3 ubiquitin protein ligase 1 OS=Homo sa | JBrowse |
