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This orthogroup contains 309 genes from 141 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 309 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR46275 | HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE | 248 / 309 | 80.3% | 100.0% of 248 | ≥80% support |
| GO | GO:0043130 Molecular Function | ubiquitin binding | 249 / 309 | 80.6% | 100.0% of 249 | ≥80% support |
| GO | GO:0005769 Cellular Component | early endosome | 248 / 309 | 80.3% | 99.6% of 249 | ≥80% support |
| GO | GO:0031623 Biological Process | receptor internalization | 248 / 309 | 80.3% | 99.6% of 249 | ≥80% support |
| GO | GO:0032456 Biological Process | endocytic recycling | 248 / 309 | 80.3% | 99.6% of 249 | ≥80% support |
| Pfam | PF12210 | Hrs_helical — Hepatocyte growth factor-regulated tyrosine kinase substrate | 218 / 309 | 70.6% | 87.2% of 250 | ≥50% support |
| Pfam | PF01363 | FYVE | 211 / 309 | 68.3% | 84.4% of 250 | ≥50% support |
| Pfam | PF00790 | VHS | 205 / 309 | 66.3% | 82.0% of 250 | ≥50% support |
| GO | GO:0035091 Molecular Function | phosphatidylinositol binding | 216 / 309 | 69.9% | 86.8% of 249 | ≥50% support |
| GO | GO:0046872 Molecular Function | metal ion binding | 212 / 309 | 68.6% | 85.1% of 249 | ≥50% support |
| KEGG | K12182 | HGS, HRS, VPS27 — Membrane trafficking | 191 / 309 | 61.8% | 98.0% of 195 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Desmophyllum pertusum | KAJ7361998.1 | KAJ7361998.1 | hypothetical protein OS493_013084 [Desmophyllum pertusum] | Q960X8 Hepatocyte growth factor-regulated tyrosine kinase substrate | JBrowse |
| Desmophyllum pertusum | KAJ7361999.1 | KAJ7361999.1 | hypothetical protein OS493_013085 [Desmophyllum pertusum] | Q0V8S0 Hepatocyte growth factor-regulated tyrosine kinase substrate | JBrowse |
| Desmophyllum pertusum | KAJ7375538.1 | KAJ7375538.1 | hypothetical protein OS493_040540, partial [Desmophyllum pertusum] | – | JBrowse |