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This orthogroup contains 296 genes from 141 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 296 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10110 | SODIUM/HYDROGEN EXCHANGER | 243 / 296 | 82.1% | 98.8% of 246 | ≥80% support |
| Pfam | PF00999 | Na_H_Exchanger — Sodium/hydrogen exchanger family | 243 / 296 | 82.1% | 99.2% of 245 | ≥80% support |
| GO | GO:0016020 Cellular Component | membrane | 245 / 296 | 82.8% | 99.6% of 246 | ≥80% support |
| GO | GO:0006812 Biological Process | monoatomic cation transport | 244 / 296 | 82.4% | 99.2% of 246 | ≥80% support |
| GO | GO:0055085 Biological Process | transmembrane transport | 244 / 296 | 82.4% | 99.2% of 246 | ≥80% support |
| GO | GO:1902600 Biological Process | proton transmembrane transport | 244 / 296 | 82.4% | 99.2% of 246 | ≥80% support |
| GO | GO:0015297 Molecular Function | antiporter activity | 243 / 296 | 82.1% | 98.8% of 246 | ≥80% support |
| GO | GO:0015385 Molecular Function | sodium:proton antiporter activity | 243 / 296 | 82.1% | 98.8% of 246 | ≥80% support |
| GO | GO:0015386 Molecular Function | potassium:proton antiporter activity | 243 / 296 | 82.1% | 98.8% of 246 | ≥80% support |
| GO | GO:0051453 Biological Process | regulation of intracellular pH | 243 / 296 | 82.1% | 98.8% of 246 | ≥80% support |
| GO | GO:0071805 Biological Process | potassium ion transmembrane transport | 243 / 296 | 82.1% | 98.8% of 246 | ≥80% support |
| GO | GO:0006814 Biological Process | sodium ion transport | 196 / 296 | 66.2% | 79.7% of 246 | ≥50% support |
| GO | GO:0006885 Biological Process | regulation of pH | 195 / 296 | 65.9% | 79.3% of 246 | ≥50% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 181 / 296 | 61.2% | 73.6% of 246 | ≥50% support |
| GO | GO:0098719 Biological Process | sodium ion import across plasma membrane | 179 / 296 | 60.5% | 72.8% of 246 | ≥50% support |
| KEGG | K14724 | SLC9A8, NHE8 — Transporters | 155 / 296 | 52.4% | 96.3% of 161 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Desmophyllum pertusum | KAJ7374637.1 | KAJ7374637.1 | Sodium/hydrogen exchanger 8 [Desmophyllum pertusum] | Q5ZJ75 Sodium/hydrogen exchanger 8 OS=Gallus gallus OX=9031 PE=2 SV | JBrowse |
| Desmophyllum pertusum | KAJ7374638.1 | KAJ7374638.1 | Sodium/hydrogen exchanger 8 [Desmophyllum pertusum] | Q9Y2E8 Sodium/hydrogen exchanger 8 OS=Homo sapiens OX=9606 GN=SLC9A | JBrowse |
