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This orthogroup contains 289 genes from 143 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 289 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| Pfam | PF02826 | 2-Hacid_dh_C — D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain | 252 / 289 | 87.2% | 96.9% of 260 | ≥80% support |
| Pfam | PF00389 | 2-Hacid_dh — D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | 232 / 289 | 80.3% | 89.2% of 260 | ≥80% support |
| GO | GO:0051287 Molecular Function | NAD binding | 258 / 289 | 89.3% | 100.0% of 258 | ≥80% support |
| GO | GO:0016616 Molecular Function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | 232 / 289 | 80.3% | 89.9% of 258 | ≥80% support |
| PANTHER | PTHR42938 | FORMATE DEHYDROGENASE 1 | 200 / 289 | 69.2% | 78.4% of 255 | ≥50% support |
| Pfam | PF19304 | PGDH_inter — D-3-phosphoglycerate dehydrogenase intervening domain | 177 / 289 | 61.3% | 68.1% of 260 | ≥50% support |
| GO | GO:0004617 Molecular Function | phosphoglycerate dehydrogenase activity | 207 / 289 | 71.6% | 80.2% of 258 | ≥50% support |
| KEGG | K00058 | serA, PHGDH — Exosome | 194 / 289 | 67.1% | 95.1% of 204 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Desmophyllum pertusum | KAJ7384166.1 | KAJ7384166.1 | hypothetical protein OS493_023495 [Desmophyllum pertusum] | Q61753 D-3-phosphoglycerate dehydrogenase OS=Mus musculus OX=10090 | JBrowse |
| Desmophyllum pertusum | KAJ7384167.1 | KAJ7384167.1 | hypothetical protein OS493_023496 [Desmophyllum pertusum] | O43175 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 G | JBrowse |
