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This orthogroup contains 285 genes from 145 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 285 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR45674 | DNA LIGASE 1/3 FAMILY MEMBER | 247 / 285 | 86.7% | 99.2% of 249 | ≥80% support |
| GO | GO:0003910 Molecular Function | DNA ligase (ATP) activity | 250 / 285 | 87.7% | 99.6% of 251 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 248 / 285 | 87.0% | 98.8% of 251 | ≥80% support |
| GO | GO:0005739 Cellular Component | mitochondrion | 247 / 285 | 86.7% | 98.4% of 251 | ≥80% support |
| GO | GO:0006266 Biological Process | DNA ligation | 247 / 285 | 86.7% | 98.4% of 251 | ≥80% support |
| GO | GO:0006273 Biological Process | lagging strand elongation | 247 / 285 | 86.7% | 98.4% of 251 | ≥80% support |
| GO | GO:0006281 Biological Process | DNA repair | 247 / 285 | 86.7% | 98.4% of 251 | ≥80% support |
| GO | GO:0006310 Biological Process | DNA recombination | 247 / 285 | 86.7% | 98.4% of 251 | ≥80% support |
| GO | GO:1903461 Biological Process | Okazaki fragment processing involved in mitotic DNA replication | 243 / 285 | 85.3% | 96.8% of 251 | ≥80% support |
| Pfam | PF01068 | DNA_ligase_A_M — ATP dependent DNA ligase domain | 207 / 285 | 72.6% | 85.2% of 243 | ≥50% support |
| Pfam | PF04675 | DNA_ligase_A_N — DNA ligase N terminus | 199 / 285 | 69.8% | 81.9% of 243 | ≥50% support |
| Pfam | PF04679 | DNA_ligase_A_C — ATP dependent DNA ligase C terminal region | 190 / 285 | 66.7% | 78.2% of 243 | ≥50% support |
| GO | GO:0005524 Molecular Function | ATP binding | 220 / 285 | 77.2% | 87.7% of 251 | ≥50% support |
| GO | GO:0003677 Molecular Function | DNA binding | 211 / 285 | 74.0% | 84.1% of 251 | ≥50% support |
| GO | GO:0003909 Molecular Function | DNA ligase activity | 205 / 285 | 71.9% | 81.7% of 251 | ≥50% support |
| GO | GO:0071897 Biological Process | DNA biosynthetic process | 191 / 285 | 67.0% | 76.1% of 251 | ≥50% support |
| KEGG | K10747 | LIG1 — DNA repair and recombination proteins | 145 / 285 | 50.9% | 96.7% of 150 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Desmophyllum pertusum | KAJ7386244.1 | KAJ7386244.1 | tRNA ligase, partial [Desmophyllum pertusum] | Q9W1H4 DNA ligase 1 OS=Drosophila melanogaster OX=7227 GN=DNAlig1 P | JBrowse |
| Desmophyllum pertusum | KAJ7386246.1 | KAJ7386246.1 | tRNA ligase [Desmophyllum pertusum] | P51892 DNA ligase 1 OS=Xenopus laevis OX=8355 GN=lig1 PE=2 SV=1 | JBrowse |
