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This orthogroup contains 281 genes from 140 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 281 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11630 | DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER | 235 / 281 | 83.6% | 99.6% of 236 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 236 / 281 | 84.0% | 100.0% of 236 | ≥80% support |
| GO | GO:0003677 Molecular Function | DNA binding | 235 / 281 | 83.6% | 99.6% of 236 | ≥80% support |
| GO | GO:0003697 Molecular Function | single-stranded DNA binding | 235 / 281 | 83.6% | 99.6% of 236 | ≥80% support |
| GO | GO:0005524 Molecular Function | ATP binding | 235 / 281 | 83.6% | 99.6% of 236 | ≥80% support |
| GO | GO:0017116 Molecular Function | single-stranded DNA helicase activity | 235 / 281 | 83.6% | 99.6% of 236 | ≥80% support |
| GO | GO:0032508 Biological Process | DNA duplex unwinding | 235 / 281 | 83.6% | 99.6% of 236 | ≥80% support |
| GO | GO:0042555 Cellular Component | MCM complex | 235 / 281 | 83.6% | 99.6% of 236 | ≥80% support |
| Pfam | PF00493 | MCM | 210 / 281 | 74.7% | 89.7% of 234 | ≥50% support |
| Pfam | PF17207 | MCM_OB — MCM OB domain | 200 / 281 | 71.2% | 85.5% of 234 | ≥50% support |
| Pfam | PF17855 | MCM_lid — MCM AAA-lid domain | 198 / 281 | 70.5% | 84.6% of 234 | ≥50% support |
| GO | GO:0016887 Molecular Function | ATP hydrolysis activity | 175 / 281 | 62.3% | 74.2% of 236 | ≥50% support |
| KEGG | K10737 | MCM8 — DNA replication proteins | 187 / 281 | 66.6% | 98.4% of 190 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Desmophyllum pertusum | KAJ7321481.1 | KAJ7321481.1 | DNA replication licensing factor mcm8 [Desmophyllum pertusum] | Q9UJA3 DNA helicase MCM8 OS=Homo sapiens OX=9606 GN=MCM8 PE=1 SV=2 | JBrowse |
