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This orthogroup contains 265 genes from 141 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 265 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR22845 | APOPTOTIC PROTEASE-ACTIVATING FACTOR 1 | 173 / 265 | 65.3% | 75.2% of 230 | ≥50% support |
| Pfam | PF00400 | WD40 — WD domain, G-beta repeat | 202 / 265 | 76.2% | 87.1% of 232 | ≥50% support |
| Pfam | PF00619 | CARD — Caspase recruitment domain | 183 / 265 | 69.1% | 78.9% of 232 | ≥50% support |
| Pfam | PF17908 | APAF1_C — APAF-1 helical domain | 182 / 265 | 68.7% | 78.5% of 232 | ≥50% support |
| Pfam | PF21296 | APAF-1-like_WHD — Apoptotic protease-activating factor 1-like, winged-helix domain | 182 / 265 | 68.7% | 78.5% of 232 | ≥50% support |
| Pfam | PF00931 | NB-ARC | 181 / 265 | 68.3% | 78.0% of 232 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 208 / 265 | 78.5% | 90.8% of 229 | ≥50% support |
| GO | GO:0042981 Biological Process | regulation of apoptotic process | 183 / 265 | 69.1% | 79.9% of 229 | ≥50% support |
| GO | GO:0043531 Molecular Function | ADP binding | 181 / 265 | 68.3% | 79.0% of 229 | ≥50% support |
| KEGG | K02084 | APAF1 — Platinum drug resistance | 146 / 265 | 55.1% | 94.8% of 154 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Desmophyllum pertusum | KAJ7373727.1 | KAJ7373727.1 | wD repeat domain [Desmophyllum pertusum] | Q5ZJW8 Denticleless protein homolog OS=Gallus gallus OX=9031 GN=DTL | JBrowse |
| Desmophyllum pertusum | KAJ7373728.1 | KAJ7373728.1 | wD repeat domain [Desmophyllum pertusum] | – | JBrowse |
| Desmophyllum pertusum | KAJ7373729.1 | KAJ7373729.1 | wD repeat domain [Desmophyllum pertusum] | O88879 Apoptotic protease-activating factor 1 OS=Mus musculus OX=10 | JBrowse |
| Desmophyllum pertusum | KAJ7373730.1 | KAJ7373730.1 | wD repeat domain [Desmophyllum pertusum] | O14727 Apoptotic protease-activating factor 1 OS=Homo sapiens OX=96 | JBrowse |
