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This orthogroup contains 253 genes from 139 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 253 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11548 | THYMIDYLATE SYNTHASE 1 | 228 / 253 | 90.1% | 100.0% of 228 | ≥80% support |
| Pfam | PF00303 | Thymidylat_synt — Thymidylate synthase | 229 / 253 | 90.5% | 100.0% of 229 | ≥80% support |
| GO | GO:0004799 Molecular Function | thymidylate synthase activity | 228 / 253 | 90.1% | 100.0% of 228 | ≥80% support |
| GO | GO:0005829 Cellular Component | cytosol | 228 / 253 | 90.1% | 100.0% of 228 | ≥80% support |
| GO | GO:0006231 Biological Process | dTMP biosynthetic process | 228 / 253 | 90.1% | 100.0% of 228 | ≥80% support |
| GO | GO:0016741 Molecular Function | transferase activity, transferring one-carbon groups | 228 / 253 | 90.1% | 100.0% of 228 | ≥80% support |
| GO | GO:0005739 Cellular Component | mitochondrion | 197 / 253 | 77.9% | 86.4% of 228 | ≥50% support |
| KEGG | K00560 | thyA, TYMS — Antifolate resistance | 190 / 253 | 75.1% | 99.0% of 192 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Desmophyllum pertusum | KAJ7373737.1 | KAJ7373737.1 | hypothetical protein OS493_011346 [Desmophyllum pertusum] | P07607 Thymidylate synthase OS=Mus musculus OX=10090 GN=Tyms PE=1 S | JBrowse |
