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This orthogroup contains 253 genes from 137 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 253 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR21077 | EME1 PROTEIN | 207 / 253 | 81.8% | 100.0% of 207 | ≥80% support |
| GO | GO:0000712 Biological Process | resolution of meiotic recombination intermediates | 207 / 253 | 81.8% | 97.6% of 212 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 207 / 253 | 81.8% | 97.6% of 212 | ≥80% support |
| GO | GO:0006281 Biological Process | DNA repair | 207 / 253 | 81.8% | 97.6% of 212 | ≥80% support |
| GO | GO:0006302 Biological Process | double-strand break repair | 207 / 253 | 81.8% | 97.6% of 212 | ≥80% support |
| GO | GO:0008821 Molecular Function | crossover junction DNA endonuclease activity | 207 / 253 | 81.8% | 97.6% of 212 | ≥80% support |
| GO | GO:0031297 Biological Process | replication fork processing | 207 / 253 | 81.8% | 97.6% of 212 | ≥80% support |
| GO | GO:0031573 Biological Process | mitotic intra-S DNA damage checkpoint signaling | 207 / 253 | 81.8% | 97.6% of 212 | ≥80% support |
| GO | GO:0048476 Cellular Component | Holliday junction resolvase complex | 207 / 253 | 81.8% | 97.6% of 212 | ≥80% support |
| Pfam | PF21292 | EME1-MUS81_C — EME1/MUS81, C-terminal | 188 / 253 | 74.3% | 95.4% of 197 | ≥50% support |
| Pfam | PF02732 | ERCC4 | 139 / 253 | 54.9% | 70.6% of 197 | ≥50% support |
| GO | GO:0003677 Molecular Function | DNA binding | 173 / 253 | 68.4% | 81.6% of 212 | ≥50% support |
| GO | GO:0004518 Molecular Function | nuclease activity | 173 / 253 | 68.4% | 81.6% of 212 | ≥50% support |
| KEGG | K10882 | EME1, MMS4 — DNA repair and recombination proteins | 145 / 253 | 57.3% | 99.3% of 146 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Desmophyllum pertusum | KAJ7386270.1 | KAJ7386270.1 | crossover junction endonuclease eme1 [Desmophyllum pertusum] | Q8BJW7 Structure-specific endonuclease subunit EME1 OS=Mus musculus | JBrowse |
| Desmophyllum pertusum | KAJ7386271.1 | KAJ7386271.1 | hypothetical protein OS493_010675 [Desmophyllum pertusum] | – | JBrowse |
