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This orthogroup contains 249 genes from 139 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 249 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR23113 | GUANINE NUCLEOTIDE EXCHANGE FACTOR | 203 / 249 | 81.5% | 100.0% of 203 | ≥80% support |
| Pfam | PF00617 | RasGEF | 202 / 249 | 81.1% | 95.7% of 211 | ≥80% support |
| GO | GO:0005085 Molecular Function | guanyl-nucleotide exchange factor activity | 206 / 249 | 82.7% | 100.0% of 206 | ≥80% support |
| GO | GO:0007264 Biological Process | small GTPase-mediated signal transduction | 206 / 249 | 82.7% | 100.0% of 206 | ≥80% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 203 / 249 | 81.5% | 98.5% of 206 | ≥80% support |
| GO | GO:0007265 Biological Process | Ras protein signal transduction | 203 / 249 | 81.5% | 98.5% of 206 | ≥80% support |
| GO | GO:0043547 Biological Process | positive regulation of GTPase activity | 203 / 249 | 81.5% | 98.5% of 206 | ≥80% support |
| Pfam | PF00169 | PH | 160 / 249 | 64.3% | 75.8% of 211 | ≥50% support |
| KEGG | K24023 | RALGPS — Domain-containing proteins not elsewhere classified | 143 / 249 | 57.4% | 99.3% of 144 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Desmophyllum pertusum | KAJ7337229.1 | KAJ7337229.1 | RasGEF [Desmophyllum pertusum] | Q4R7W3 Ras-specific guanine nucleotide-releasing factor RalGPS2 OS= | JBrowse |
| Desmophyllum pertusum | KAJ7337256.1 | KAJ7337256.1 | RasGEF [Desmophyllum pertusum] | – | JBrowse |
