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This orthogroup contains 248 genes from 137 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 248 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10073 | DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL | 211 / 248 | 85.1% | 99.5% of 212 | ≥80% support |
| GO | GO:0006298 Biological Process | mismatch repair | 211 / 248 | 85.1% | 99.5% of 212 | ≥80% support |
| GO | GO:0016887 Molecular Function | ATP hydrolysis activity | 211 / 248 | 85.1% | 99.5% of 212 | ≥80% support |
| GO | GO:0032300 Cellular Component | mismatch repair complex | 211 / 248 | 85.1% | 99.5% of 212 | ≥80% support |
| GO | GO:0140664 Molecular Function | ATP-dependent DNA damage sensor activity | 211 / 248 | 85.1% | 99.5% of 212 | ≥80% support |
| GO | GO:0005524 Molecular Function | ATP binding | 206 / 248 | 83.1% | 97.2% of 212 | ≥80% support |
| Pfam | PF08676 | MutL_C — MutL C terminal dimerisation domain | 170 / 248 | 68.6% | 85.4% of 199 | ≥50% support |
| Pfam | PF13589 | HATPase_c_3 — Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase | 132 / 248 | 53.2% | 66.3% of 199 | ≥50% support |
| GO | GO:0030983 Molecular Function | mismatched DNA binding | 145 / 248 | 58.5% | 68.4% of 212 | ≥50% support |
| KEGG | K08739 | MLH3 — DNA repair and recombination proteins | 126 / 248 | 50.8% | 97.7% of 129 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Desmophyllum pertusum | KAJ7365537.1 | KAJ7365537.1 | DNA mismatch repair protein [Desmophyllum pertusum] | Q9UHC1 DNA mismatch repair protein Mlh3 OS=Homo sapiens OX=9606 GN= | JBrowse |
| Desmophyllum pertusum | KAJ7365538.1 | KAJ7365538.1 | hypothetical protein OS493_005650 [Desmophyllum pertusum] | Q9UHC1 DNA mismatch repair protein Mlh3 OS=Homo sapiens OX=9606 GN= | JBrowse |
