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This orthogroup contains 245 genes from 144 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 245 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10292 | CLATHRIN HEAVY CHAIN RELATED | 217 / 245 | 88.6% | 100.0% of 217 | ≥80% support |
| GO | GO:0006898 Biological Process | receptor-mediated endocytosis | 216 / 245 | 88.2% | 99.5% of 217 | ≥80% support |
| GO | GO:0032051 Molecular Function | clathrin light chain binding | 216 / 245 | 88.2% | 99.5% of 217 | ≥80% support |
| GO | GO:0071439 Cellular Component | clathrin complex | 216 / 245 | 88.2% | 99.5% of 217 | ≥80% support |
| GO | GO:0006886 Biological Process | intracellular protein transport | 214 / 245 | 87.4% | 98.6% of 217 | ≥80% support |
| GO | GO:0016192 Biological Process | vesicle-mediated transport | 214 / 245 | 87.4% | 98.6% of 217 | ≥80% support |
| GO | GO:0045334 Cellular Component | clathrin-coated endocytic vesicle | 204 / 245 | 83.3% | 94.0% of 217 | ≥80% support |
| Pfam | PF00637 | Clathrin | 192 / 245 | 78.4% | 89.7% of 214 | ≥50% support |
| Pfam | PF01394 | Clathrin_propel — Clathrin propeller repeat | 184 / 245 | 75.1% | 86.0% of 214 | ≥50% support |
| Pfam | PF13838 | Clathrin_H_link — Clathrin-H-link | 176 / 245 | 71.8% | 82.2% of 214 | ≥50% support |
| Pfam | PF09268 | Clathrin-link — Clathrin, heavy-chain linker | 135 / 245 | 55.1% | 63.1% of 214 | ≥50% support |
| GO | GO:0005198 Molecular Function | structural molecule activity | 192 / 245 | 78.4% | 88.5% of 217 | ≥50% support |
| GO | GO:0030130 Cellular Component | clathrin coat of trans-Golgi network vesicle | 192 / 245 | 78.4% | 88.5% of 217 | ≥50% support |
| GO | GO:0030132 Cellular Component | clathrin coat of coated pit | 192 / 245 | 78.4% | 88.5% of 217 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 191 / 245 | 78.0% | 88.0% of 217 | ≥50% support |
| KEGG | K04646 | CLTC — Exosome | 178 / 245 | 72.7% | 97.8% of 182 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Desmophyllum pertusum | KAJ7378730.1 | KAJ7378730.1 | hypothetical protein OS493_021312 [Desmophyllum pertusum] | Q68FD5 Clathrin heavy chain 1 OS=Mus musculus OX=10090 GN=Cltc PE=1 | JBrowse |
