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This orthogroup contains 243 genes from 144 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 243 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10631 | N 2 ,N 2 -DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE | 204 / 243 | 84.0% | 100.0% of 204 | ≥80% support |
| Pfam | PF02005 | TRM — N2,N2-dimethylguanosine tRNA methyltransferase | 204 / 243 | 84.0% | 97.6% of 209 | ≥80% support |
| GO | GO:0003723 Molecular Function | RNA binding | 206 / 243 | 84.8% | 98.1% of 210 | ≥80% support |
| GO | GO:0008033 Biological Process | tRNA processing | 206 / 243 | 84.8% | 98.1% of 210 | ≥80% support |
| GO | GO:0160102 Molecular Function | tRNA (guanine(10)-N2)-methyltransferase activity | 206 / 243 | 84.8% | 98.1% of 210 | ≥80% support |
| GO | GO:0002940 Biological Process | tRNA N2-guanine methylation | 204 / 243 | 84.0% | 97.1% of 210 | ≥80% support |
| GO | GO:0004809 Molecular Function | obsolete tRNA (guanine-N2-)-methyltransferase activity | 204 / 243 | 84.0% | 97.1% of 210 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 204 / 243 | 84.0% | 97.1% of 210 | ≥80% support |
| GO | GO:0046872 Molecular Function | metal ion binding | 166 / 243 | 68.3% | 79.1% of 210 | ≥50% support |
| KEGG | K00555 | TRMT1, trm1 — Transfer RNA biogenesis | 160 / 243 | 65.8% | 98.8% of 162 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Desmophyllum pertusum | KAJ7390711.1 | KAJ7390711.1 | tRNA methyltransferase 1 [Desmophyllum pertusum] | Q9NXH9 tRNA (guanine(26)-N(2))-dimethyltransferase OS=Homo sapiens | JBrowse |