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This orthogroup contains 237 genes from 140 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 237 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR12604 | KU AUTOANTIGEN DNA HELICASE | 206 / 237 | 86.9% | 99.0% of 208 | ≥80% support |
| Pfam | PF02735 | Ku | 194 / 237 | 81.9% | 93.3% of 208 | ≥80% support |
| Pfam | PF03730 | Ku_C — Ku70/Ku80 C-terminal arm | 194 / 237 | 81.9% | 93.3% of 208 | ≥80% support |
| GO | GO:0006303 Biological Process | double-strand break repair via nonhomologous end joining | 209 / 237 | 88.2% | 100.0% of 209 | ≥80% support |
| GO | GO:0000723 Biological Process | telomere maintenance | 208 / 237 | 87.8% | 99.5% of 209 | ≥80% support |
| GO | GO:0042162 Molecular Function | telomeric DNA binding | 208 / 237 | 87.8% | 99.5% of 209 | ≥80% support |
| GO | GO:0043564 Cellular Component | Ku70:Ku80 complex | 208 / 237 | 87.8% | 99.5% of 209 | ≥80% support |
| GO | GO:0003690 Molecular Function | double-stranded DNA binding | 206 / 237 | 86.9% | 98.6% of 209 | ≥80% support |
| GO | GO:0003677 Molecular Function | DNA binding | 203 / 237 | 85.7% | 97.1% of 209 | ≥80% support |
| GO | GO:0003678 Molecular Function | DNA helicase activity | 194 / 237 | 81.9% | 92.8% of 209 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 192 / 237 | 81.0% | 91.9% of 209 | ≥80% support |
| GO | GO:0003684 Molecular Function | damaged DNA binding | 191 / 237 | 80.6% | 91.4% of 209 | ≥80% support |
| Pfam | PF03731 | Ku_N — Ku70/Ku80 N-terminal alpha/beta domain | 186 / 237 | 78.5% | 89.4% of 208 | ≥50% support |
| KEGG | K10884 | XRCC6, KU70, G22P1 — DNA repair and recombination proteins | 171 / 237 | 72.2% | 97.7% of 175 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Desmophyllum pertusum | KAJ7370949.1 | KAJ7370949.1 | X-ray repair cross-complementing protein 6 [Desmophyllum pertusum] | P12956 X-ray repair cross-complementing protein 6 OS=Homo sapiens O | JBrowse |
