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This orthogroup contains 233 genes from 138 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 233 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10337 | SHC TRANSFORMING PROTEIN | 195 / 233 | 83.7% | 96.5% of 202 | ≥80% support |
| GO | GO:0019901 Molecular Function | protein kinase binding | 196 / 233 | 84.1% | 97.0% of 202 | ≥80% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 190 / 233 | 81.6% | 94.1% of 202 | ≥80% support |
| GO | GO:0030971 Molecular Function | receptor tyrosine kinase binding | 190 / 233 | 81.6% | 94.1% of 202 | ≥80% support |
| GO | GO:0007169 Biological Process | cell surface receptor protein tyrosine kinase signaling pathway | 189 / 233 | 81.1% | 93.6% of 202 | ≥80% support |
| Pfam | PF00017 | SH2 | 181 / 233 | 77.7% | 89.6% of 202 | ≥50% support |
| Pfam | PF00640 | PID | 180 / 233 | 77.3% | 89.1% of 202 | ≥50% support |
| GO | GO:0035556 Biological Process | intracellular signal transduction | 178 / 233 | 76.4% | 88.1% of 202 | ≥50% support |
| KEGG | K06279 | SHC1 — Endocrine resistance | 134 / 233 | 57.5% | 98.5% of 136 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Desmophyllum pertusum | KAJ7365799.1 | KAJ7365799.1 | SHC (Src y 2 domain containing) transforming protein [Desmophyllum pertusum] | Q8AY68 SHC-transforming protein 1 OS=Xenopus laevis OX=8355 GN=shc1 | JBrowse |
